SCHEMBL9400341

SCHEMBL9400341

O=C(Nc1cccc(O)c1)Nc1cccc(O)c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.70
CYP1A2 P05177 1/20 0.70
BAZ1A Q9NRL2 1/20 0.69
KMT2A Q03164 4/20 0.66
MEN1 O00255 2/20 0.66
TRPV1 Q8NER1 1/20 0.63
CNR1 P21554 1/20 0.62
DDX3X O00571 1/20 0.61
LMNA P02545 1/20 0.61
MAPT P10636 1/20 0.61
HTT P42858 1/20 0.61
GRIK1 P39086 1/20 0.59
MGLL Q99685 1/20 0.59
EPHX2 P34913 2/20 0.58
DYRK1A Q13627 1/20 0.58
DYRK1B Q9Y463 1/20 0.58
TP53 P04637 2/20 0.58
NPC1 O15118 1/20 0.58
MAPK1 P28482 1/20 0.58
RAB9A P51151 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7098404 0.94 TP53 (0.68) ALDH1A1CYP1A2BAZ1AKMT2AMEN1
SCHEMBL30589624 0.89 MEN1 (0.82) ALDH1A1KMT2AMEN1TRPV1CNR1
SCHEMBL5455619 0.89 BAZ1A (0.58) ALDH1A1CYP1A2BAZ1AKMT2AMEN1
SCHEMBL28914350 0.89 MEN1 (0.82) ALDH1A1KMT2AMEN1TRPV1CNR1
SCHEMBL22025929 0.88 ALDH1A1 (0.61) ALDH1A1CYP1A2BAZ1AKMT2AMEN1
SCHEMBL7097165 0.88 ALDH1A1 (0.67) ALDH1A1CYP1A2BAZ1AKMT2AMEN1
SCHEMBL22588913 0.87 NPC1 (0.69) ALDH1A1CYP1A2BAZ1AKMT2AMEN1
SCHEMBL22588925 0.87 ALDH1A1 (0.83) ALDH1A1CYP1A2BAZ1AKMT2AMEN1
SCHEMBL31078919 0.87 BAZ1A (0.69) ALDH1A1CYP1A2BAZ1AKMT2AMEN1
SCHEMBL29473480 0.86 ALDH1A1 (0.70) ALDH1A1CYP1A2BAZ1AKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4076530-A Dry photographic copying method for producing Te images FUJI PHOTO FILM CO., LTD. (JA) 1978-02-28 US claimed
US-5372917-A Excellent color forming property, storage stability and recorded image preservability; pyrazolone derivatives KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1994-12-13 US disclosed
US-4076530-A Dry photographic copying method for producing Te images FUJI PHOTO FILM CO., LTD. (JA) 1978-02-28 US disclosed