SCHEMBL30665993

SCHEMBL30665993

CC(C)(C)OC(=O)CC[C@H](NC(=O)CNC(=O)[C@H](Cc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1)NC(=O)OC(C)(C)C)C(=O)NCC(=O)O

nearest known ligand 0.44

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ NMBR P28336 1/20 0.44
▸ SIRT2 Q8IXJ6 12/20 0.43
▸ CTSS P25774 3/20 0.40
▸ CTSK P43235 2/20 0.40
▸ CTSL P07711 1/20 0.40
▸ CTSB P07858 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30277394 0.92 NMBR (0.44) NMBRSIRT2CTSS
SCHEMBL30250367 0.91 NMBR (0.42) NMBRSIRT2CTSSCTSKCTSL
SCHEMBL29427176 0.90 NMBR (0.51) NMBRSIRT2CTSSCTSKCTSL
SCHEMBL29427178 0.90 NMBR (0.51) NMBRSIRT2CTSSCTSKCTSL
SCHEMBL31414641 0.88 NMBR (0.46) NMBRSIRT2CTSSCTSKCTSL
SCHEMBL30107533 0.87 REN (0.41) NMBRSIRT2
SCHEMBL30384691 0.86 NMBR (0.40) NMBRSIRT2
SCHEMBL29475292 0.84 NMBR (0.40) NMBRSIRT2CTSSCTSKCTSL
SCHEMBL31094878 0.83 SIRT2 (0.41) NMBRSIRT2
SCHEMBL30107538 0.83 SIRT2 (0.44) NMBRSIRT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118005766-B Solid phase synthesis method of Glepaglutide 杭州信海医药科技有限公司 2024-09-27 — — CN disclosed
CN-118005766-B Solid phase synthesis method of Glepaglutide 杭州信海医药科技有限公司 2024-09-27 — — CN disclosed
CN-118005766-A Solid phase synthesis method of Glepaglutide 杭州信海医药科技有限公司 2024-05-10 — — CN disclosed
CN-118005766-A Solid phase synthesis method of Glepaglutide 杭州信海医药科技有限公司 2024-05-10 — — CN disclosed
CN-116751278-B Preparation method of Glepaglutide 杭州信海医药科技有限公司 2024-02-13 — — CN disclosed
CN-116751278-A Preparation method of Glepaglutide 杭州信海医药科技有限公司 2023-09-15 — — CN disclosed
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