SCHEMBL30277394

SCHEMBL30277394

C[C@H](NC(=O)[C@H](Cc1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1)NC(=O)OC(C)(C)C)C(=O)N[C@@H](CCC(=O)OC(C)(C)C)C(=O)NCC(=O)O

nearest known ligand 0.44

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ NMBR P28336 1/20 0.44
▸ SIRT2 Q8IXJ6 12/20 0.42
▸ REN P00797 5/20 0.41
▸ PSMB10 P40306 1/20 0.39
▸ PSMB2 P49721 1/20 0.39
▸ CTSS P25774 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30665993 0.92 NMBR (0.44) NMBRSIRT2CTSS
SCHEMBL30107538 0.92 SIRT2 (0.44) NMBRSIRT2REN
SCHEMBL30107533 0.90 REN (0.41) NMBRSIRT2REN
SCHEMBL31094878 0.90 SIRT2 (0.41) NMBRSIRT2
SCHEMBL30250367 0.89 NMBR (0.42) NMBRSIRT2CTSS
SCHEMBL29427176 0.88 NMBR (0.51) NMBRSIRT2CTSS
SCHEMBL29427178 0.88 NMBR (0.51) NMBRSIRT2CTSS
SCHEMBL31614440 0.86 REN (0.41) RENPSMB10PSMB2
SCHEMBL29475292 0.84 NMBR (0.40) NMBRSIRT2RENCTSS
SCHEMBL30053690 0.83 NMBR (0.49) NMBRSIRT2CTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12441760-B2 Amino diacids containing peptide modifiers CHEMICAL & BIOPHARMACEUTICAL LABORATORIES OF PATRAS S.A. (GR) 2025-10-14 — — US disclosed
US-20240002433-A1 AMINO DIACIDS CONTAINING PEPTIDE MODIFIERS CHEMICAL & BIOPHARMACEUTICAL LABORATORIES OF PATRAS S.A. (GR) 2024-01-04 — — US disclosed
US-11634455-B2 Amino diacids containing peptide modifiers CHEMICAL & BIOPHARMACEUTICAL LABORATORIES OF PATRAS S.A. (GR) 2023-04-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12441760-B2 Amino diacids containing peptide modifiers PTMS, PEPD, NGLY1 NMBR 1681/4885SIRT2 3109/4885REN 141/4885
US-11634455-B2 Amino diacids containing peptide modifiers PTMS, PEPD, VIP NMBR 1654/4885SIRT2 3138/4885REN 133/4885
US-20240002433-A1 AMINO DIACIDS CONTAINING PEPTIDE MODIFIERS PTMS, PEPD, NGLY1 NMBR 1681/4885SIRT2 3109/4885REN 141/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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