Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 10/20 | 0.39 |
| ▸ | MPEG1 | Q2M385 | 7/20 | 0.39 |
| ▸ | CDC25A | P30304 | 6/20 | 0.39 |
| ▸ | CDC25B | P30305 | 6/20 | 0.39 |
| ▸ | CDC25C | P30307 | 5/20 | 0.39 |
| ▸ | XIAP | P98170 | 2/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7051769 | 1.00 | ALDH1A1 (0.43) | ALDH1A1TDP1MAPTTHRBLMNA | |
| SCHEMBL114204 | 0.98 | ALDH1A1 (0.41) | ALDH1A1TDP1MAPTTHRBLMNA | |
| SCHEMBL131405 | 0.92 | ALDH1A1 (0.35) | ALDH1A1TDP1MAPTTHRBLMNA | |
| Acetic Acid SCHEMBL9004863 | 0.89 | ALDH1A1 (0.44) | ALDH1A1TDP1MAPTTHRBLMNA | |
| SCHEMBL20819043 | 0.86 | ALDH1A1 (0.39) | ALDH1A1TDP1MAPTTHRBLMNA | |
| SCHEMBL10385817 | 0.83 | GAA (0.36) | ALDH1A1 | |
| SCHEMBL16276017 | 0.79 | — | — | |
| SCHEMBL19052887 | 0.79 | ACHE (0.33) | ALDH1A1TDP1MAPTTHRBLMNA | |
| SCHEMBL8570683 | 0.79 | ALDH1A1 (0.33) | ALDH1A1TDP1MAPTTHRBLMNA | |
| SCHEMBL8570684 | 0.79 | ALDH1A1 (0.33) | ALDH1A1TDP1MAPTTHRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150011749-A1 | USE OF CERTAIN METAL-ACCUMULATING PLANTS FOR THE PERFORMANCE OF ORGANIC CHEMISTRY REACTIONS | UNIVERSITE MONTPELLIER 2 SCIENCES ET TECHNIQUES (FR) | 2015-01-08 | — | — | US | disclosed |
| US-20150011749-A1 | USE OF CERTAIN METAL-ACCUMULATING PLANTS FOR THE PERFORMANCE OF ORGANIC CHEMISTRY REACTIONS | UNIVERSITE MONTPELLIER 2 SCIENCES ET TECHNIQUES (FR) | 2015-01-08 | — | — | US | disclosed |
| US-20100113460-A1 | Organic Compounds | GIVAUDAN SA (CH) | 2010-05-06 | — | — | US | disclosed |
| US-20100113460-A1 | Organic Compounds | GIVAUDAN SA (CH) | 2010-05-06 | — | — | US | disclosed |
| US-20100113460-A1 | Organic Compounds | GIVAUDAN SA (CH) | 2010-05-06 | — | — | US | disclosed |
| EP-2139354-A2 | ORGANIC COMPOUNDS | Givaudan SA (CH) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008116339-A2 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2008-10-02 | — | — | WO | disclosed |
| WO-2008116339-A2 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2008-10-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113460-A1 | Organic Compounds | CYP2B6, CYP2A6, CYP2A13 | ALDH1A1 78/4885TDP1 1152/4885MAPT 3924/4885 |
| US-20150011749-A1 | USE OF CERTAIN METAL-ACCUMULATING PLANTS FOR THE PERFORMANCE OF ORGANIC CHEMISTRY REACTIONS | ME1, OSGEP, AGL | ALDH1A1 912/4885TDP1 1530/4885MAPT 533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.