SCHEMBL29476089

SCHEMBL29476089

O=C1OC(=O)c2c(F)ccc(F)c21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
TSHR P16473 2/20 0.39
ALDH1A1 P00352 1/20 0.39
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
AHR P35869 1/20 0.33
TYMS P04818 1/20 0.33
TTR P02766 1/20 0.32
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31
NPC1 O15118 1/20 0.31
CASP3 P42574 1/20 0.31
RAB9A P51151 1/20 0.31
SENP8 Q96LD8 1/20 0.31
SENP7 Q9BQF6 1/20 0.31
SENP6 Q9GZR1 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL581013 1.00 ALOX15 (0.41) ALOX15TDP1TSHRALDH1A1CA1
SCHEMBL19585963 0.86 ACHE (0.36) ALOX15TDP1TSHRALDH1A1CA1
SCHEMBL18789227 0.86 ALDH1A1 (0.65) ALOX15TDP1TSHRALDH1A1CA1
SCHEMBL855199 0.86 TSHR (0.41) ALOX15TDP1TSHRALDH1A1L3MBTL1
SCHEMBL7483193 0.86 ALOX15 (0.32) ALOX15TDP1TSHRALDH1A1
SCHEMBL855012 0.86 ALDH1A1 (0.41) ALOX15TDP1TSHRALDH1A1TYMS
SCHEMBL23914626 0.83 CA1 (0.31) CA1CA2CA7CA9
SCHEMBL19585504 0.82 AR (0.36) F7F3
SCHEMBL29411884 0.78 ALOX15 (0.50) ALOX15TDP1CA1CA2CA7
SCHEMBL263099 0.78 ALOX15 (0.50) ALOX15TDP1CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116867942-B Method for preparing lignocellulose and reinforced composite material thereof 浙江大学 2024-12-27 CN claimed
CN-118638459-A Waterproof and wear-resistant raincoat applique material and preparation method thereof 玉山县美斯旅游用品有限公司 2024-09-13 CN claimed
CN-115926397-B Method for preparing degradable nanocellulose reinforced composite material 浙江大学 2024-08-27 CN claimed
CN-115819630-B Method for preparing high-charge nanocellulose 浙江大学衢州研究院 2024-07-05 CN claimed
CN-116867942-A Method for preparing lignocellulose and reinforced composite material thereof 浙江大学 2023-10-10 CN claimed
CN-116367672-A Preparation method of perovskite device 宣城先进光伏技术有限公司 2023-06-30 CN claimed
CN-115926397-A Method for preparing degradable nanocellulose reinforced composite materials 浙江大学 2023-04-07 CN claimed
CN-115819630-A Method for preparing high-charge-capacity nanocellulose 浙江大学衢州研究院 2023-03-21 CN claimed
CN-115606033-A Electrochemical device and electronic device comprising same 宁德新能源科技有限公司(CN) 2023-01-13 CN claimed
CN-114085224-A Preparation method of pyrrolopyrimidine compound 北京普祺医药科技有限公司 2022-02-25 CN claimed
US-20250092468-A1 BIOMARKERS OF RESPONSE TO HIF-2-ALPHA INHIBITION IN CANCER AND METHODS FOR THE USE THEREOF THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-03-20 US disclosed
US-12234516-B2 Biomarkers of response to HIF-2-alpha inhibition in cancer and methods for the use thereof THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-02-25 US disclosed
CN-119264119-A Preparation method and application of FLT3 degradation agent based on pyrazinecarboxamide skeleton 中国科学院上海有机化学研究所 2025-01-07 CN disclosed
CN-116867942-B Method for preparing lignocellulose and reinforced composite material thereof 浙江大学 2024-12-27 CN disclosed
CN-119137113-A THR beta analogues and uses thereof 马德里加尔制药公司 2024-12-13 CN disclosed
CN-109867661-B Amide compounds for regulating WNT signal pathway and application thereof 中国医学科学院药物研究所 2022-07-19 CN disclosed
CN-110325531-B Benzenesulfonamides and their use as therapeutic agents 泽农医药公司 2022-05-27 CN disclosed
CN-114442431-A Photosensitive resin composition containing polyimide precursor 上海玟昕科技有限公司 2022-05-06 CN disclosed
CN-114415472-A Photosensitive resin composition containing polyimide precursor 上海玟昕科技有限公司 2022-04-29 CN disclosed
CN-114085224-A Preparation method of pyrrolopyrimidine compound 北京普祺医药科技有限公司 2022-02-25 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12234516-B2 Biomarkers of response to HIF-2-alpha inhibition in cancer and methods for the use thereof HIF1AN, HIF1A, EGLN2 ALOX15 3735/4885TDP1 3395/4885TSHR 2547/4885
US-20250092468-A1 BIOMARKERS OF RESPONSE TO HIF-2-ALPHA INHIBITION IN CANCER AND METHODS FOR THE USE THEREOF HIF1AN, HIF1A, EGLN2 ALOX15 3735/4885TDP1 3395/4885TSHR 2547/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.