Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.30 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.30 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.30 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL855646 | 0.86 | TSHR (0.52) | TSHRALDH1A1MEN1POLBMAPT | |
| SCHEMBL29688935 | 0.86 | TSHR (0.52) | TSHRALDH1A1MEN1POLBMAPT | |
| SCHEMBL29476089 | 0.86 | ALOX15 (0.41) | TSHRALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL581013 | 0.86 | ALOX15 (0.41) | TSHRALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL7483193 | 0.74 | ALOX15 (0.32) | TSHRALDH1A1ALOX15TDP1 | |
| SCHEMBL19585963 | 0.74 | ACHE (0.36) | TSHRALDH1A1L3MBTL1ALOX15TDP1 | |
| SCHEMBL855012 | 0.74 | ALDH1A1 (0.41) | TSHRALDH1A1L3MBTL1ALOX15TDP1 | |
| SCHEMBL18789227 | 0.74 | ALDH1A1 (0.65) | TSHRALDH1A1POLBMAPTL3MBTL1 | |
| SCHEMBL23914626 | 0.71 | CA1 (0.31) | — | |
| SCHEMBL854984 | 0.71 | TSHR (0.43) | TSHRALDH1A1MAPTALOX15TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8604221-B2 | Production method of halogen-substituted phthalide | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-12-10 | — | — | US | disclosed |
| US-20120142946-A1 | PRODUCTION METHOD OF HALOGEN-SUBSTITUTED PHTHALIDE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-06-07 | — | — | US | disclosed |
| EP-2433933-A1 | PRODUCTION METHOD OF HALOGEN-SUBSTITUTED PHTHALIDE | Sumitomo Chemical Company, Limited (JP) | 2012-03-28 | — | — | EP | disclosed |