SCHEMBL29476409

SCHEMBL29476409

CC(C)C[C@@H](NC(=O)[C@@H](N)CS)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CS)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ KISS1R Q969F8 20/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31620051 0.94 TUBB4A (0.51) KISS1R
SCHEMBL29476495 0.94 TUBB4A (0.51) KISS1R
SCHEMBL29531021 0.94 TUBB4A (0.51) KISS1R
SCHEMBL29476562 0.94 MC4R (0.50) KISS1R
SCHEMBL29476617 0.94 MC4R (0.50) KISS1R
SCHEMBL29476582 0.93 C5AR1 (0.55) KISS1R
SCHEMBL31555126 0.93 MC4R (0.49) KISS1R
SCHEMBL30104393 0.93 CTSL (0.47) —
SCHEMBL30218268 0.93 KISS1R (0.53) KISS1R
SCHEMBL30264960 0.93 CTSL (0.49) KISS1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118271400-A Peptide composition 节奏制药公司 2024-07-02 — — CN claimed
CN-118240012-A Peptide composition 节奏制药公司 2024-06-25 — — CN claimed
CN-105492456-B Peptide composition 节奏制药公司 2024-11-01 — — CN disclosed
CN-118271400-A Peptide composition 节奏制药公司 2024-07-02 — — CN disclosed
CN-118240012-A Peptide composition 节奏制药公司 2024-06-25 — — CN disclosed
EP-4216979-A1 METHODS OF TREATING MELANOCORTIN-4 RECEPTOR PATHWAY-ASSOCIATED DISORDERS Rhythm Pharmaceuticals, Inc. (US) 2023-08-02 — — EP disclosed
CN-116507353-A Methods of treating melanocortin-4 receptor pathway-related disorders 节奏制药公司 2023-07-28 — — CN disclosed
CN-115957297-A Pharmaceutical composition 节奏制药公司 2023-04-14 — — CN disclosed
CN-115957296-A Pharmaceutical composition 节奏制药公司 2023-04-14 — — CN disclosed
JP-2022084844-A PEPTIDE COMPOSITIONS リズム・ファーマシューティカルズ・インコーポレイテッド 2022-06-07 — — JP disclosed
WO-2022067086-A1 METHODS OF TREATING MELANOCORTIN-4 RECEPTOR PATHWAY-ASSOCIATED DISORDERS RHYTHM PHARMACEUTICALS, INC. (US) 2022-03-31 — — WO disclosed
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