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Sugi Predict / Compounds / SCHEMBL29476582

SCHEMBL29476582

SCHEMBL29476582

CC(C)[C@@H](NC(=O)[C@@H](N)CS)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CS)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ C5AR1 P21730 2/20 0.55
▸ IL23R Q5VWK5 12/20 0.52
▸ KISS1R Q969F8 2/20 0.50
▸ CD47 Q08722 1/20 0.48
▸ GLP1R P43220 3/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29476694 0.95 C5AR1 (0.51) C5AR1IL23RGLP1R
SCHEMBL29531021 0.94 TUBB4A (0.51) C5AR1IL23RKISS1R
SCHEMBL31620051 0.94 TUBB4A (0.51) C5AR1IL23RKISS1R
SCHEMBL29476495 0.94 TUBB4A (0.51) C5AR1IL23RKISS1R
SCHEMBL29476409 0.93 KISS1R (0.54) KISS1R
SCHEMBL29476617 0.93 MC4R (0.50) C5AR1KISS1R
SCHEMBL29476562 0.93 MC4R (0.50) C5AR1KISS1R
SCHEMBL30080698 0.93 C5AR1 (0.55) C5AR1IL23RCD47
SCHEMBL31555126 0.93 MC4R (0.49) C5AR1KISS1R
SCHEMBL30104393 0.93 CTSL (0.47) C5AR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118271400-A Peptide composition 节奏制药公司 2024-07-02 — — CN claimed
CN-118240012-A Peptide composition 节奏制药公司 2024-06-25 — — CN claimed
CN-105492456-B Peptide composition 节奏制药公司 2024-11-01 — — CN disclosed
CN-118271400-A Peptide composition 节奏制药公司 2024-07-02 — — CN disclosed
CN-118240012-A Peptide composition 节奏制药公司 2024-06-25 — — CN disclosed
EP-4216979-A1 METHODS OF TREATING MELANOCORTIN-4 RECEPTOR PATHWAY-ASSOCIATED DISORDERS Rhythm Pharmaceuticals, Inc. (US) 2023-08-02 — — EP disclosed
CN-116507353-A Methods of treating melanocortin-4 receptor pathway-related disorders 节奏制药公司 2023-07-28 — — CN disclosed
CN-115957297-A Pharmaceutical composition 节奏制药公司 2023-04-14 — — CN disclosed
CN-115957296-A Pharmaceutical composition 节奏制药公司 2023-04-14 — — CN disclosed
WO-2022067086-A1 METHODS OF TREATING MELANOCORTIN-4 RECEPTOR PATHWAY-ASSOCIATED DISORDERS RHYTHM PHARMACEUTICALS, INC. (US) 2022-03-31 — — WO disclosed
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