Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 13/20 | 0.44 |
| ▸ | ADK | P55263 | 5/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.41 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17106708 | 0.91 | METTL3 (0.45) | METTL3ADKPRMT5RAPGEF3 | |
| SCHEMBL24313507 | 0.84 | METTL3 (0.46) | METTL3ADKPRMT5RAPGEF3 | |
| SCHEMBL29611126 | 0.84 | METTL3 (0.46) | METTL3ADKPRMT5RAPGEF3 | |
| SCHEMBL17106819 | 0.83 | PRMT5 (0.48) | METTL3ADKPRMT5RAPGEF3 | |
| SCHEMBL17106864 | 0.82 | PRMT5 (0.47) | METTL3ADKPRMT5RAPGEF3 | |
| SCHEMBL29478315 | 0.81 | PRMT5 (0.31) | METTL3PRMT5 | |
| SCHEMBL17106678 | 0.80 | PRMT5 (0.39) | METTL3PRMT5 | |
| SCHEMBL17106705 | 0.80 | METTL3 (0.43) | METTL3ADKPRMT5 | |
| SCHEMBL17114360 | 0.80 | METTL3 (0.43) | METTL3ADKPRMT5 | |
| SCHEMBL17111271 | 0.79 | PRMT5 (0.45) | METTL3ADKPRMT5RAPGEF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022074391-A1 | COMPOUNDS INHIBITORS OF METTL3 | STORM THERAPEUTICS LIMITED (GB) | 2022-04-14 | — | — | WO | disclosed |