Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 11/20 | 0.46 |
| ▸ | ADK | P55263 | 4/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.42 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.41 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.41 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.39 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.39 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.39 |
| ▸ | NNMT | P40261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29611126 | 1.00 | METTL3 (0.46) | METTL3ADKPRMT5RAPGEF3HASPIN | |
| SCHEMBL17106708 | 0.87 | METTL3 (0.45) | METTL3ADKPRMT5RAPGEF3 | |
| SCHEMBL17106819 | 0.84 | PRMT5 (0.48) | METTL3ADKPRMT5RAPGEF3 | |
| SCHEMBL29478306 | 0.84 | METTL3 (0.44) | METTL3ADKPRMT5RAPGEF3 | |
| SCHEMBL29610964 | 0.83 | METTL3 (0.55) | METTL3ADKPRMT5HASPIN | |
| SCHEMBL17106864 | 0.81 | PRMT5 (0.47) | METTL3ADKPRMT5RAPGEF3 | |
| SCHEMBL29611067 | 0.79 | ADK (0.48) | METTL3ADKPRMT5HASPINDOT1L | |
| SCHEMBL24313824 | 0.79 | ADK (0.48) | METTL3ADKPRMT5HASPINDOT1L | |
| SCHEMBL17111271 | 0.79 | PRMT5 (0.45) | METTL3ADKPRMT5RAPGEF3 | |
| SCHEMBL20938367 | 0.77 | ADK (0.50) | METTL3ADKPRMT5RAPGEF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081739-A1 | METTL3 MODULATORS | ACCENT THERAPEUTICS, INC. (US) | 2022-04-21 | — | — | WO | disclosed |