Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 11/20 | 0.48 |
| ▸ | ADK | P55263 | 3/20 | 0.38 |
| ▸ | SRC | P12931 | 5/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.37 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24293550 | 1.00 | METTL3 (0.48) | METTL3ADKSRCEGFRMETTL14 | |
| SCHEMBL24293871 | 0.90 | METTL3 (0.40) | METTL3ADKSRCEGFR | |
| SCHEMBL24293646 | 0.77 | SRC (0.47) | ADKSRCEGFR | |
| SCHEMBL29478323 | 0.76 | METTL3 (0.49) | METTL3METTL14 | |
| SCHEMBL31618062 | 0.76 | ADK (0.44) | METTL3ADKRAPGEF3 | |
| SCHEMBL31617944 | 0.76 | ADK (0.44) | METTL3ADKRAPGEF3 | |
| SCHEMBL25048738 | 0.76 | METTL3 (0.46) | METTL3ADKMETTL14RAPGEF3 | |
| SCHEMBL29478318 | 0.75 | METTL3 (0.42) | METTL3SRCMETTL14 | |
| SCHEMBL19667609 | 0.73 | SRC (0.37) | METTL3SRCEGFR | |
| SCHEMBL30207875 | 0.73 | SRC (0.37) | METTL3SRCEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022074391-A1 | COMPOUNDS INHIBITORS OF METTL3 | STORM THERAPEUTICS LIMITED (GB) | 2022-04-14 | — | — | WO | disclosed |