SCHEMBL29479214

SCHEMBL29479214

CC(=O)c1ccc2c(ccn2[Si](C)(C)C)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.42
MAPT P10636 3/20 0.40
ALDH1A1 P00352 2/20 0.40
HPGD P15428 2/20 0.40
FGFR1 P11362 1/20 0.39
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
POLB P06746 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
MAOB P27338 1/20 0.38
RPS6KA5 O75582 1/20 0.37
TUBB4A P04350 1/20 0.37
TUBB P07437 1/20 0.37
TUBA3C P0DPH7 1/20 0.37
TUBA1B P68363 1/20 0.37
TUBA4A P68366 1/20 0.37
TUBB4B P68371 1/20 0.37
TUBB3 Q13509 1/20 0.37
TUBB2A Q13885 1/20 0.37
TUBB8 Q3ZCM7 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2610251 0.77 MAOB (0.57) CYP2A6MAPTMAOBTUBB4ATUBB
SCHEMBL16492908 0.73 TUBB4A (0.59) CYP2A6TUBB4ATUBBTUBA3CTUBA1B
SCHEMBL17275595 0.70 RAPGEF4 (0.45) HPGDSMN1; SMN2RAPGEF4
SCHEMBL2610324 0.69 HTR2A (0.48) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL18960579 0.69 HTR2C (0.56) PLGPLAU
SCHEMBL122499 0.69 KCNH2 (0.57) MAPTALDH1A1HPGDFGFR1NPC1
SCHEMBL834744 0.69 CYP2A6 (0.68) CYP2A6MAPTALDH1A1HPGDNPC1
SCHEMBL9033835 0.68 OPRD1 (0.44)
SCHEMBL1623656 0.68 PIK3CD (0.45) CYP2A6MAPTALDH1A1HPGDNPC1
SCHEMBL4410330 0.68 MAOB (0.59) MAPTALDH1A1HPGDNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112708902-B Method for electrochemically synthesizing indole compounds 中国科学技术大学 2022-03-01 CN disclosed