SCHEMBL2948064

SCHEMBL2948064

CCc1c(N)cc(O)c(C)c1O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.36
ALDH1A1 P00352 4/20 0.34
GAA P10253 3/20 0.34
HSD17B10 Q99714 3/20 0.34
ALOX15 P16050 2/20 0.34
KDM4E B2RXH2 2/20 0.34
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
ESR1 P03372 2/20 0.33
AR P10275 1/20 0.33
ESR2 Q92731 1/20 0.33
HPGD P15428 3/20 0.32
PKM P14618 2/20 0.32
USP2 O75604 1/20 0.32
HTT P42858 2/20 0.31
NPC1 O15118 1/20 0.31
MAPK1 P28482 1/20 0.31
RAB9A P51151 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
CYP3A4 P08684 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27696644 0.85 ESR1 (0.38) ACHEALDH1A1GAAHSD17B10ALOX15
SCHEMBL25306227 0.83 ALDH1A1 (0.39) ALDH1A1GAAHSD17B10KDM4ELMNA
SCHEMBL28853125 0.83 SELL (0.36) ALDH1A1GAAHSD17B10ALOX15KDM4E
SCHEMBL27638429 0.81 ALDH1A1 (0.32) ALDH1A1GAAHSD17B10ALOX15KDM4E
SCHEMBL13736318 0.78 ACHE (0.39) ACHEALDH1A1GAAHSD17B10ALOX15
SCHEMBL16908700 0.76 HPGD (0.34) ACHEALDH1A1GAAHSD17B10ALOX15
SCHEMBL2222707 0.73 SELL (0.42) ACHEESR1ESR2HPGDHTT
SCHEMBL14686010 0.72 ACHE (0.37) ACHEALDH1A1GAAHSD17B10ALOX15
SCHEMBL15781982 0.72 ACHE (0.46) ACHEALDH1A1HSD17B10ALOX15KDM4E
SCHEMBL423627 0.72 ALDH1A1 (0.37) ALDH1A1HSD17B10ALOX15KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11285094-B2 Nail coating compositions and methods having powdered activator HAILE DANNY LEE (US) 2022-03-29 US claimed
US-20200030221-A1 NAIL COATING COMPOSITIONS AND METHODS HAVING POWDERED ACTIVATOR HAILE DANNY LEE (US) 2020-01-30 US claimed
CN-110527079-A Add the flame retardant polyether polyol and preparation method thereof of hydramine WUHAN INST TECHNOLOGY 2019-12-03 CN claimed
EP-2912131-B1 ADHESIVE COMPOSITIONS Henkel IP & Holding GmbH (DE) 2018-06-06 EP claimed
US-9657203-B2 Adhesive compositions Henkel IP & Holding GmbH (DE) 2017-05-23 US claimed
US-9574118-B2 Adhesive compositions Henkel IP & Holding GmbH (DE) 2017-02-21 US claimed
US-20150225626-A1 ADHESIVE COMPOSITIONS HENKEL AG & CO. KGAA (DE) 2015-08-13 US claimed
US-20140235758-A1 ADHESIVE COMPOSITIONS Henkel US IP LLC (US) 2014-08-21 US claimed
WO-2013074265-A1 ADHESIVE COMPOSITIONS HENKEL CORPORATION (US) 2013-05-23 WO claimed
US-20100065210-A1 FLOWABLE NON-SAGGING ADHESIVE COMPOSITIONS HENKEL CORPORATION (US) 2010-03-18 US claimed
WO-2008057414-A1 FLOWABLE, NON-SAGGING ADHESIVE COMPOSITIONS HENKEL CORPORATION (US) 2008-05-15 WO claimed
CN-1291090-A Composition for making temporary crowns and bridges KERR CORP (US) 2001-04-11 CN claimed
US-20240384142-A1 (METH)ACRYLATE-BASED TOUGHENED ADHESIVES HENKEL AG & CO. KGAA (DE) 2024-11-21 US disclosed
WO-2023147115-A1 (METH)ACRYLATE-BASED TOUGHENED ADHESIVES HENKEL AG & CO. KGAA (DE) 2023-08-03 WO disclosed
US-11285094-B2 Nail coating compositions and methods having powdered activator HAILE DANNY LEE (US) 2022-03-29 US disclosed
EP-3508541-B1 TWO-COMPONENT ADHESIVE COMPOSITION LG CHEMICAL LTD (KR) 2021-07-14 EP disclosed
WO-1991015183-A1 COMPOSITE DENTAL CEMENT COMPOSITION CONTAINING TITANIUM ESSENTIAL DENTAL SYSTEMS, INC. (US) 1991-10-17 WO disclosed
US-4813875-A QUICK-SETTING FREE RADICAL POLYMERIZABLE RESIN DENTSPLY RESEARCH & DEVELOPMENT CORP. (US) 1989-03-21 US disclosed
EP-0269071-A2 Chain extended urethane diacrylate and dental impression formation DENTSPLY INTERNATIONAL, INC. (US) 1988-06-01 EP disclosed
US-4572920-A ANION EXCHANGE MONOMER, ACRYLIC MONOMER FOR PREVENTION OF DENTAL CARIES RESEARCH CORPORATION (US) 1986-02-25 US disclosed