Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21065052 | 0.85 | CASP1 (0.59) | ACHEALDH1A1MAPTGAABACE1 | |
| SCHEMBL3676098 | 0.80 | BACE1 (0.37) | HTTNPC1HPGDMAPK1RAB9A | |
| SCHEMBL11315486 | 0.79 | ACHE (0.42) | ACHEHTTNPC1HPGDMAPK1 | |
| SCHEMBL15781982 | 0.79 | ACHE (0.46) | ACHEHTTNPC1HPGDMAPK1 | |
| SCHEMBL2222707 | 0.75 | SELL (0.42) | ACHEHTTNPC1HPGDMAPK1 | |
| SCHEMBL27696644 | 0.74 | ESR1 (0.38) | ACHEHTTNPC1HPGDMAPK1 | |
| SCHEMBL28401269 | 0.73 | HPGD (0.41) | HTTNPC1HPGDMAPK1RAB9A | |
| SCHEMBL9861229 | 0.72 | ALOX15 (0.39) | HTTMAPK1ALDH1A1MAPTGAA | |
| SCHEMBL2948064 | 0.72 | ACHE (0.36) | ACHEHTTNPC1HPGDMAPK1 | |
| SCHEMBL28122020 | 0.72 | ALDH1A1 (0.42) | HTTNPC1HPGDMAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2556816-A2 | Permanent hair dye in the form of foam | "Aroma" Plc. (BG) | 2013-02-13 | — | — | EP | disclosed |