Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 20/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23086201 | 1.00 | SLC6A3 (0.46) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL21456828 | 0.88 | SLC6A3 (0.53) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL24155283 | 0.80 | SLC6A3 (0.42) | SLC6A3SLC6A4 | |
| SCHEMBL29480839 | 0.74 | SLC6A3 (0.42) | SLC6A3SLC6A4 | |
| SCHEMBL29480840 | 0.72 | SLC6A3 (0.44) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL23086203 | 0.72 | SLC6A3 (0.44) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL24136532 | 0.70 | IDO1 (0.35) | SLC6A3SLC6A4 | |
| SCHEMBL16011850 | 0.66 | SLC6A3 (0.51) | SLC6A3 | |
| SCHEMBL28741653 | 0.65 | SLC6A3 (0.37) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL19939826 | 0.63 | ALDH1A1 (0.41) | SLC6A3SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12612374-B2 | Thiazole and diphenyl substituted sulfoxides for use in improving cognition functions and against addictions to substances | COGMOTIV FLEXCO (AT) | 2026-04-28 | — | — | US | disclosed |
| US-20220324821-A1 | THIAZOLE AND DIPHENYL SUBSTITUTED SULFOXIDES FOR USE IN IMPROVING COGNITION FUNCTIONS AND AGAINST ADDICTIONS TO SUBSTANCES | COGMOTIV FLEXCO (AT) | 2022-10-13 | — | — | US | disclosed |
| CN-114401948-A | Thiazole and diphenyl substituted sulfoxides for improving cognitive function and combating substance addiction | 红牛有限公司 | 2022-04-26 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12612374-B2 | Thiazole and diphenyl substituted sulfoxides for use in improving cognition functions and against addictions to substances | CHAT, PNMT, CHRM5 | SLC6A3 9/4885SLC6A2 63/4885SLC6A4 105/4885 |
| US-20220324821-A1 | THIAZOLE AND DIPHENYL SUBSTITUTED SULFOXIDES FOR USE IN IMPROVING COGNITION FUNCTIONS AND AGAINST ADDICTIONS TO SUBSTANCES | COMT, TST, PNMT | SLC6A3 18/4885SLC6A2 67/4885SLC6A4 172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.