Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 4/20 | 0.48 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.46 |
| ▸ | DNTT | P04053 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.44 |
| ▸ | GALR3 | O60755 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2948238 | 1.00 | PTGER4 (0.48) | PTGER4PTGER3TRPA1ALDH1A1MEN1 | |
| SCHEMBL2738718 | 0.90 | TRPA1 (0.46) | PTGER4PTGER3TRPA1ALDH1A1MEN1 | |
| SCHEMBL3439784 | 0.90 | TRPA1 (0.46) | PTGER4PTGER3TRPA1ALDH1A1MEN1 | |
| SCHEMBL10020985 | 0.90 | TRPA1 (0.46) | PTGER4PTGER3TRPA1ALDH1A1MEN1 | |
| SCHEMBL10052300 | 0.88 | TRPA1 (0.44) | PTGER4PTGER3TRPA1ALDH1A1MEN1 | |
| SCHEMBL2760341 | 0.88 | TRPA1 (0.44) | PTGER4PTGER3TRPA1ALDH1A1MEN1 | |
| SCHEMBL2948519 | 0.87 | TRPA1 (0.61) | PTGER4PTGER3TRPA1ALDH1A1MEN1 | |
| SCHEMBL2948516 | 0.87 | TRPA1 (0.61) | PTGER4PTGER3TRPA1ALDH1A1MEN1 | |
| SCHEMBL3439785 | 0.86 | PTGER4 (0.42) | PTGER4PTGER3TRPA1ALDH1A1MEN1 | |
| SCHEMBL10020993 | 0.86 | PTGER4 (0.42) | PTGER4PTGER3TRPA1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7759399-B2 | Pharmaceutical compositions | CRAWFORD HEALTHCARE HOLDINGS LIMITED (GB) | 2010-07-20 | — | — | US | disclosed |
| US-20060252839-A1 | Pharmaceutical compositions | BIOGEM S.C.A.R.L. (IT) | 2006-11-09 | — | — | US | disclosed |
| EP-1487789-A2 | IMPROVEMENTS IN PHARMACEUTICAL COMPOSITIONS | Charterhouse Therapeutics Ltd. (GB) | 2004-12-22 | — | — | EP | disclosed |
| WO-2003082813-A2 | IMPROVEMENTS IN PHARMACEUTICAL COMPOSITIONS | CHARTERHOUSE THERAPEUTICS LIMITED (GB) | 2003-10-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060252839-A1 | Pharmaceutical compositions | ADK, SYMPK, CYP2J2 | PTGER4 645/4885PTGER3 284/4885TRPA1 1929/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.