SCHEMBL29482592

SCHEMBL29482592

CCS(=O)(=O)c1cc(CC#N)cnc1-c1nc2cc(C(F)(F)F)nnc2n1C

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ USP1 O94782 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20553672 0.87 ELANE (0.34) —
SCHEMBL20482178 0.86 S1PR1 (0.34) USP1
SCHEMBL29482594 0.86 S1PR1 (0.34) USP1
SCHEMBL20482176 0.86 POLB (0.32) —
SCHEMBL30490812 0.86 POLB (0.32) —
SCHEMBL17609311 0.85 POLB (0.40) —
SCHEMBL25203415 0.84 LRRK2 (0.30) —
SCHEMBL30177546 0.84 LRRK2 (0.30) —
SCHEMBL20567951 0.84 POLB (0.32) USP1
SCHEMBL17688763 0.84 PTGS2 (0.32) USP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11440910-B2 Pesticidally active heterocyclic derivatives with sulfur containing substituents SYNGENTA PARTICIPATIONS AG (CH) 2022-09-13 — — US disclosed
EP-3585770-B1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS SYNGENTA PARTICIPATIONS AG (CH) 2022-03-23 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11440910-B2 Pesticidally active heterocyclic derivatives with sulfur containing substituents DDT, ACHE, SQOR USP1 1486/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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