Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 7/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 5/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29484159 | 0.83 | PLA2G1B (0.68) | MEN1KMT2AALOX12ALDH1A1SMN1; SMN2 | |
| SCHEMBL3063087 | 0.83 | ALDH1A1 (0.68) | MEN1KMT2AALOX12ALDH1A1SMN1; SMN2 | |
| SCHEMBL10056165 | 0.83 | CYP2C19 (0.73) | CYP2C9CYP2C19MEN1KMT2AALDH1A1 | |
| SCHEMBL625166 | 0.82 | CYP2C19 (1.00) | CYP2C9CYP2C19MEN1KMT2AALOX12 | |
| SCHEMBL29484166 | 0.81 | ALDH1A1 (0.56) | MEN1KMT2AALOX12ALDH1A1SMN1; SMN2 | |
| SCHEMBL29484175 | 0.80 | ALDH1A1 (0.71) | CYP2C9CYP2C19MEN1KMT2AALOX12 | |
| SCHEMBL17794373 | 0.79 | GAA (0.67) | CYP2C9CYP2C19MEN1KMT2AALOX12 | |
| SCHEMBL14860298 | 0.78 | ALDH1A1 (0.80) | CYP2C9CYP2C19MEN1KMT2AALOX12 | |
| SCHEMBL6564185 | 0.78 | IDO1 (0.67) | CYP2C9CYP2C19MEN1KMT2AALOX12 | |
| Iodide SCHEMBL15015678 | 0.77 | IDO1 (0.65) | CYP2C9CYP2C19MEN1KMT2AALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022055940-A1 | VISTA INHIBITORS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2022-03-17 | — | — | WO | disclosed |