Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G1B | P04054 | 2/20 | 0.68 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.64 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29484161 | 0.83 | CYP2C9 (0.69) | ALDH1A1LMNAMEN1KMT2AALOX12 | |
| SCHEMBL3063087 | 0.83 | ALDH1A1 (0.68) | ALDH1A1LMNAMEN1KMT2AALOX12 | |
| SCHEMBL689542 | 0.82 | CYP2C19 (0.66) | PLA2G1BATG4BALDH1A1LMNAKMT2A | |
| SCHEMBL29484166 | 0.81 | ALDH1A1 (0.56) | ALDH1A1LMNAMEN1KMT2AALOX12 | |
| SCHEMBL29484175 | 0.80 | ALDH1A1 (0.71) | ALDH1A1LMNAMEN1KMT2AALOX12 | |
| SCHEMBL1959781 | 0.78 | PLA2G1B (0.70) | PLA2G1BATG4BALDH1A1LMNAMEN1 | |
| SCHEMBL7657194 | 0.76 | ALDH1A1 (0.66) | PLA2G1BATG4BALDH1A1LMNAMEN1 | |
| SCHEMBL29484158 | 0.76 | ALDH1A1 (0.44) | PLA2G1BATG4BALDH1A1LMNAMEN1 | |
| SCHEMBL20496874 | 0.75 | PLA2G1B (0.78) | PLA2G1BATG4BALDH1A1LMNAMEN1 | |
| SCHEMBL18415459 | 0.74 | LMNA (0.66) | PLA2G1BATG4BALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022055940-A1 | VISTA INHIBITORS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2022-03-17 | — | — | WO | disclosed |