Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | MITF | O75030 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ADAMTS5 | Q9UNA0 | 5/20 | 0.56 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3063087 | 0.90 | ALDH1A1 (0.68) | ALDH1A1MITFALOX12KMT2AMEN1 | |
| SCHEMBL8245493 | 0.83 | LMNA (0.64) | ALDH1A1KMT2AMEN1GAALMNA | |
| SCHEMBL29484161 | 0.81 | CYP2C9 (0.69) | ALDH1A1ALOX12KMT2AMEN1GAA | |
| SCHEMBL29484159 | 0.81 | PLA2G1B (0.68) | ALDH1A1ALOX12KMT2AMEN1GAA | |
| SCHEMBL3426065 | 0.80 | KMT2A (0.57) | ALDH1A1ALOX12KMT2AMEN1GAA | |
| SCHEMBL29484175 | 0.77 | ALDH1A1 (0.71) | ALDH1A1ALOX12KMT2AMEN1GAA | |
| SCHEMBL20496895 | 0.77 | ALOX12 (0.63) | ALDH1A1ALOX12KMT2AMEN1GAA | |
| SCHEMBL11374387 | 0.77 | ALDH1A1 (0.69) | ALDH1A1MITFALOX12KMT2AMEN1 | |
| SCHEMBL2893277 | 0.76 | ALDH1A1 (0.72) | ALDH1A1MITFALOX12KMT2AMEN1 | |
| SCHEMBL3059505 | 0.76 | ALDH1A1 (0.70) | ALDH1A1MITFALOX12KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022055940-A1 | VISTA INHIBITORS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2022-03-17 | — | — | WO | disclosed |