Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.69 |
| ▸ | NPC1 | O15118 | 4/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiourea SCHEMBL1991944 | 0.82 | MAPT (0.73) | EPHX1NPC1MAPTKDM4EALDH1A1 | |
| SCHEMBL4395392 | 0.81 | MAPT (0.61) | EPHX1NPC1MAPTKDM4EALDH1A1 | |
| SCHEMBL11634169 | 0.81 | ALDH1A1 (0.66) | NPC1MAPTKDM4EALDH1A1RAB9A | |
| SCHEMBL3083065 | 0.81 | EPHX1 (0.67) | EPHX1NPC1MAPTKDM4EALDH1A1 | |
| SCHEMBL28597947 | 0.81 | NPC1 (0.70) | EPHX1NPC1MAPTALDH1A1RAB9A | |
| SCHEMBL6811493 | 0.80 | ALDH1A1 (0.67) | EPHX1NPC1MAPTKDM4EALDH1A1 | |
| SCHEMBL526059 | 0.80 | MAPT (0.63) | EPHX1NPC1MAPTKDM4EALDH1A1 | |
| SCHEMBL224279 | 0.80 | NPC1 (1.00) | EPHX1NPC1MAPTKDM4EALDH1A1 | |
| SCHEMBL11449846 | 0.80 | IDO1 (0.66) | NPC1MAPTALDH1A1RAB9AHTT | |
| SCHEMBL5445907 | 0.80 | MAPT (0.75) | EPHX1NPC1MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022055940-A1 | VISTA INHIBITORS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2022-03-17 | — | — | WO | disclosed |