SCHEMBL29484201

SCHEMBL29484201

CC1(C)CC(=O)C2=C(C1)OC=CC2c1ccc(Cl)cc1Cl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 4/20 0.41
ALDH1A1 P00352 4/20 0.41
GAA P10253 3/20 0.41
MAPT P10636 3/20 0.41
KDM4E B2RXH2 2/20 0.41
HPGD P15428 2/20 0.41
HSD17B10 Q99714 2/20 0.41
HTT P42858 2/20 0.41
NPC1 O15118 1/20 0.41
USP2 O75604 1/20 0.41
LMNA P02545 1/20 0.41
TP53 P04637 1/20 0.41
PKM P14618 1/20 0.41
ALOX15 P16050 1/20 0.41
ALOX12 P18054 1/20 0.41
MAPK1 P28482 1/20 0.41
AGTR1 P30556 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29484199 0.84 MEN1 (0.45) NPSR1ALDH1A1GAAMAPTKDM4E
SCHEMBL29484200 0.84 MEN1 (0.45) NPSR1ALDH1A1GAAMAPTKDM4E
SCHEMBL29484202 0.83 OPRD1 (0.44) NPSR1ALDH1A1GAAMAPTKDM4E
SCHEMBL29484198 0.73 MEN1 (0.45) NPSR1ALDH1A1GAAMAPTKDM4E
SCHEMBL29484194 0.73 OPRM1 (0.48) NPSR1ALDH1A1GAAMAPTKDM4E
SCHEMBL8186663 0.72 GSK3B (0.55) NPSR1ALDH1A1GAAMAPTKDM4E
SCHEMBL29484195 0.72 ALDH1A1 (0.54) NPSR1ALDH1A1GAAMAPTKDM4E
SCHEMBL29484197 0.71 ACHE (0.49) ALDH1A1GAAMAPTKDM4EHPGD
SCHEMBL29484196 0.71 ACHE (0.49) ALDH1A1GAAMAPTKDM4EHPGD
SCHEMBL10737556 0.68 KMT2A (0.47) NPSR1ALDH1A1GAAMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111875591-B Method for catalytic synthesis of drug intermediate 3-benzo [ d ] imidazole benzopyrone derivative 马鞍山市泰博化工科技有限公司 2022-03-15 CN disclosed