Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.86 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.78 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.78 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.78 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.78 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.78 |
| ▸ | PRNP | P04156 | 1/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | NPY2R | P49146 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2228522 | 1.00 | RAB9A (0.86) | RAB9ACYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL2353265 | 0.82 | CYP1A2 (0.67) | RAB9ACYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL13186475 | 0.77 | L3MBTL1 (0.65) | RAB9ACYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL13186477 | 0.76 | MEN1 (0.74) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL13186804 | 0.76 | MEN1 (0.85) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL13186789 | 0.75 | MEN1 (0.73) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL13947279 | 0.75 | KDM4E (0.79) | RAB9ACYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL15919820 | 0.74 | KMT2A (1.00) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL30287914 | 0.73 | RAB9A (0.74) | RAB9ACYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL13102332 | 0.73 | RAB9A (0.74) | RAB9ACYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11466272-B2 | Nucleic acid suppressing expression of APCS | KYOWA KIRIN CO., LTD. (JP) | 2022-10-11 | — | — | US | disclosed |
| US-20220127605-A1 | NUCLEIC ACID CONJUGATE | KYOWA KIRIN CO., LTD. (JP) | 2022-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220127605-A1 | NUCLEIC ACID CONJUGATE | NSUN3, NSUN2, RNASEH1 | RAB9A 4096/4885CYP1A2 4823/4885CYP3A4 4873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.