Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.45 |
| ▸ | MPO | P05164 | 9/20 | 0.43 |
| ▸ | LPL | P06858 | 1/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30182153 | 0.83 | HTR1D (0.42) | HTR2AHTR2CIDO1HTR1AKMT2A | |
| SCHEMBL3180731 | 0.79 | GPR84 (0.50) | GPR84HTR2AHTR2CTRPM8IDO1 | |
| SCHEMBL25508375 | 0.78 | IDO1 (0.39) | GPR84LPLLIPGIDO1 | |
| SCHEMBL29414051 | 0.78 | ATM (0.44) | GPR84LPLLIPGHTR2AHTR2C | |
| SCHEMBL2111365 | 0.78 | ATM (0.44) | GPR84LPLLIPGHTR2AHTR2C | |
| SCHEMBL25508360 | 0.76 | GPR84 (0.45) | GPR84LPLLIPG | |
| SCHEMBL14685262 | 0.74 | GSK3A (0.38) | LPLLIPGHTR2AHTR1A | |
| SCHEMBL32678331 | 0.72 | LPL (0.56) | LPLLIPGIDO1 | |
| SCHEMBL32678332 | 0.72 | LPL (0.56) | LPLLIPGIDO1 | |
| SCHEMBL3154179 | 0.72 | LPL (0.47) | LPLLIPGHTR2AHTR2CIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107624112-B | Small molecule inhibitors of lactate dehydrogenase and methods of use thereof | 美国政府健康及人类服务部 | 2022-03-04 | — | — | CN | disclosed |