Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 9/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.38 |
| ▸ | CCKAR | P32238 | 1/20 | 0.34 |
| ▸ | CCKBR | P32239 | 1/20 | 0.34 |
| ▸ | SELE | P16581 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29832449 | 0.88 | KEAP1 (0.37) | KEAP1FOLH1SELE | |
| SCHEMBL29832692 | 0.88 | VHL (0.34) | KEAP1SELE | |
| SCHEMBL2084290 | 0.86 | FOLH1 (0.42) | FOLH1SELE | |
| SCHEMBL29832959 | 0.85 | KEAP1 (0.34) | KEAP1SELE | |
| SCHEMBL29832360 | 0.83 | KEAP1 (0.36) | KEAP1SELE | |
| SCHEMBL30358533 | 0.78 | KEAP1 (0.48) | KEAP1 | |
| SCHEMBL29408359 | 0.75 | DPP4 (0.49) | KEAP1FOLH1 | |
| SCHEMBL29485657 | 0.75 | KEAP1 (0.43) | KEAP1FOLH1 | |
| SCHEMBL29720815 | 0.74 | NAALAD2 (0.46) | FOLH1 | |
| SCHEMBL32689886 | 0.74 | KEAP1 (0.46) | KEAP1CCKARCCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114364691-B | Peptides as inhibitors of fibrotic matrix accumulation | 马克斯·普朗克科学促进学会 | 2023-12-12 | — | — | CN | disclosed |
| US-20220267378-A1 | PEPTIDES AS INHIBITORS OF FIBROTIC MATRIX ACCUMULATION | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2022-08-25 | — | — | US | disclosed |
| EP-3996694-A1 | PEPTIDES AS INHIBITORS OF FIBROTIC MATRIX ACCUMULATION | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2022-05-18 | — | — | EP | disclosed |
| CN-114364691-A | Peptides as inhibitors of fibrotic matrix accumulation | 马克斯·普朗克科学促进学会 | 2022-04-15 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220267378-A1 | PEPTIDES AS INHIBITORS OF FIBROTIC MATRIX ACCUMULATION | INHA, GLS, AGXT | KEAP1 2478/4885FOLH1 1156/4885CCKAR 2002/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.