Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 4/20 | 0.45 |
| ▸ | CCR9 | P51686 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | ECE1 | P42892 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2945848 | 0.81 | ALDH1A1 (0.44) | KDM4EALDH1A1HSD17B10PTGER1PTGDR2 | |
| SCHEMBL2950130 | 0.74 | MAPT (0.43) | KDM4EALDH1A1HSD17B10PTGDR2ECE1 | |
| SCHEMBL2945336 | 0.74 | PPARG (0.52) | PTGER1ALKBH1 | |
| SCHEMBL6018268 | 0.74 | CCR2 (0.59) | CCR2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL2943282 | 0.71 | MAPT (0.42) | KDM4EALDH1A1HSD17B10PTGDR2 | |
| SCHEMBL3033844 | 0.70 | CCR2 (0.40) | CCR2CCR9GPR35ECE1 | |
| SCHEMBL4600630 | 0.70 | CCR2 (0.55) | CCR2CCR9KDM4EALDH1A1HPGD | |
| SCHEMBL4392732 | 0.70 | GPR35 (0.53) | CCR2CCR9GPR35 | |
| SCHEMBL9714527 | 0.69 | GRM2 (0.43) | KDM4EALDH1A1PTGER1JAK3AURKA | |
| SCHEMBL2944416 | 0.69 | HDAC1 (0.40) | ALDH1A1PTGER1PTGDR2ECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558611-B1 | HIV-INTEGRASE INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND METHODS FOR THEIR USE | PFIZER (US) | 2010-01-06 | — | — | EP | claimed |