SCHEMBL29487566

SCHEMBL29487566

Fc1ccc(F)c(Br)c1F

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
GPR84 Q9NQS5 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL313506 1.00 CES2 (0.36) CES2CES1GPR84
SCHEMBL1426701 0.82 CYP2A6 (0.33)
SCHEMBL246708 0.81 CES2 (0.39) CES2CES1GPR84
SCHEMBL1770614 0.81 KDM1A (0.35)
SCHEMBL30906668 0.77
SCHEMBL5019963 0.77 CA3 (0.39) CES2CES1
SCHEMBL8979083 0.77
SCHEMBL4623500 0.77 ACHE (0.36)
SCHEMBL11131552 0.77 TP53 (0.32) CES2CES1
SCHEMBL31035242 0.77 CES2 (0.31) CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026090477-A1 HELICASE INHIBITORS AND USES THEREOF KIMIA THERAPEUTICS, INC. (US) 2026-04-30 WO disclosed
CN-111936476-B Aromatic compound and preparation method and application thereof 上海致根医药科技有限公司 2024-04-02 CN disclosed
EP-4298098-A1 SULFONYL BENZAMIDE DERIVATIVES AS BCL-2 INHIBITORS Ascentage Pharma (Suzhou) Co., Ltd. (CN) 2024-01-03 EP disclosed
CN-114835704-B Sulfonylbenzamide derivatives as BCL-2 inhibitors 苏州亚盛药业有限公司 2023-10-27 CN disclosed
CN-116685594-A Triarylborane catalysts and methods for selective hydrosilylation of esters and lactones using the same 阿尔迪斯化学有限责任公司 2023-09-01 CN disclosed
CN-116367574-A Organic light emitting diode and organic light emitting display device having the same 乐金显示有限公司 2023-06-30 CN disclosed
CN-116283539-A Preparation method of 2,4, 5-trifluoro phenylacetic acid 安庆朗坤药业有限公司 2023-06-23 CN disclosed
CN-116113294-A Organic electroluminescent device and application thereof 季华恒烨(佛山)电子材料有限公司 2023-05-12 CN disclosed
CN-113666951-B Boron-nitrogen compound, organic electroluminescent composition and organic electroluminescent device comprising same 季华实验室 2022-12-20 CN disclosed
WO-2022161496-A1 SULFONYL BENZAMIDE DERIVATIVES AS BCL-2 INHIBITORS ASCENTAGE PHARMA (SUZHOU) CO., LTD. (CN) 2022-08-04 WO disclosed
CN-114835704-A Sulfonylbenzamide derivatives as BCL-2 inhibitors 苏州亚盛药业有限公司 2022-08-02 CN disclosed
CN-114181136-A Substituted piperidine compounds and uses thereof 武田药品工业株式会社 2022-03-15 CN disclosed