Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC15A1 | P46059 | 2/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11121985 | 0.93 | SLC15A1 (0.43) | SLC15A1SLC1A1SLC1A3SLC1A2MEN1 | |
| SCHEMBL10901317 | 0.84 | SLC15A1 (0.43) | SLC15A1SLC1A1SLC1A3SLC1A2MEN1 | |
| SCHEMBL11280290 | 0.84 | SLC15A1 (0.43) | SLC15A1SLC1A1SLC1A3SLC1A2MEN1 | |
| SCHEMBL5181819 | 0.83 | ALDH1A1 (0.47) | SLC1A1SLC1A3SLC1A2MEN1CYP1A2 | |
| SCHEMBL28790921 | 0.80 | SLC15A1 (0.50) | SLC15A1SLC1A1SLC1A3SLC1A2MEN1 | |
| SCHEMBL11433447 | 0.80 | SLC1A1 (0.41) | SLC15A1SLC1A1SLC1A3ALDH1A1LTA4H | |
| SCHEMBL30116131 | 0.79 | ALDH1A1 (0.41) | SLC15A1SLC1A1SLC1A3SLC1A2MEN1 | |
| SCHEMBL10805335 | 0.79 | CA4 (0.40) | SLC15A1SLC1A1SLC1A3KMT2AABCB1 | |
| SCHEMBL11782102 | 0.77 | TPSAB1 (0.52) | SLC1A1SLC1A3 | |
| SCHEMBL6671876 | 0.77 | SLC15A1 (0.43) | SLC15A1SLC1A1SLC1A3SLC1A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12559731-B2 | Mutated PglB oligosaccharyl transferase enzymes | GLAXOSMITHKLINE BIOLOGICALS SA (BE) | 2026-02-24 | — | — | US | disclosed |
| US-20250270520-A1 | MUTATED PGLB OLIGOSACCHARYLTRANSFERASE ENZYMES | GLAXOSMITHKLINE BIOLOGICALS SA (BE) | 2025-08-28 | — | — | US | disclosed |
| EP-4389908-A2 | MUTATED PGLB OLIGOSACCHARYLTRANSFERASE ENZYMES | GlaxoSmithKline Biologicals S.A. (BE) | 2024-06-26 | — | — | EP | disclosed |
| EP-4010467-B1 | MUTATED PGLB OLIGOSACCHARYLTRANSFERASE ENZYMES | GLAXOSMITHKLINE BIOLOGICALS SA (BE) | 2024-04-24 | — | — | EP | disclosed |
| EP-4291673-A2 | MUTATED PGLB OLIGOSACCHARYLTRANSFERASE ENZYMES | GlaxoSmithKline Biologicals SA (BE) | 2023-12-20 | — | — | EP | disclosed |
| US-20220403347-A1 | MUTATED PGLB OLIGOSACCHARYLTRANSFERASE ENZYMES | GLAXOSMITHKLINE BIOLOGICALS SA (BE) | 2022-12-22 | — | — | US | disclosed |
| WO-2022171679-A2 | PROTEIN | GLAXOSMITHKLINE BIOLOGICALS SA (BE) | 2022-08-18 | — | — | WO | disclosed |
| EP-4010467-A1 | MUTATED PGLB OLIGOSACCHARYLTRANSFERASE ENZYMES | GlaxoSmithKline Biologicals SA (BE) | 2022-06-15 | — | — | EP | disclosed |
| CN-114207122-A | Mutant PGLB oligosaccharyl transferases | 葛兰素史克生物有限公司 | 2022-03-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12559731-B2 | Mutated PglB oligosaccharyl transferase enzymes | OSTC, PGLS, O60361 | SLC15A1 931/4885SLC1A1 2441/4885SLC1A3 1615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.