Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.40 |
| ▸ | RELA | Q04206 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13419786 | 0.81 | PTGDR2 (0.50) | PTGDR2KMT2AKDM4EPOLBALDH1A1 | |
| SCHEMBL28686804 | 0.74 | CCR5 (0.46) | KMT2AMEN1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL29488290 | 0.74 | CCR5 (0.46) | KMT2AMEN1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL8709054 | 0.73 | CYP3A4 (0.47) | PTGDR2MAPTKDM4EALDH1A1LRRK2 | |
| SCHEMBL28330058 | 0.72 | MAPT (0.52) | RAB9ANPC1KMT2AMEN1OPRK1 | |
| SCHEMBL11711621 | 0.71 | RAB9A (0.53) | RAB9ANPC1KMT2AMEN1OPRK1 | |
| SCHEMBL11711627 | 0.71 | RAB9A (0.53) | RAB9ANPC1KMT2AMEN1OPRK1 | |
| SCHEMBL29994104 | 0.71 | GSTA1 (0.61) | RAB9ANPC1KMT2AMEN1OPRK1 | |
| SCHEMBL8709730 | 0.71 | GSTA1 (0.61) | RAB9ANPC1KMT2AMEN1OPRK1 | |
| SCHEMBL29488296 | 0.71 | MAPT (0.59) | RAB9ANPC1KMT2AMEN1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110746345-B | Synthesis method of 2- (2-amino-5-bromo-benzoyl) pyridine | 苏州永健生物医药有限公司 | 2022-03-04 | — | — | CN | claimed |
| CN-110746345-B | Synthesis method of 2- (2-amino-5-bromo-benzoyl) pyridine | 苏州永健生物医药有限公司 | 2022-03-04 | — | — | CN | disclosed |