Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 4/20 | 0.32 |
| ▸ | THRB | P10828 | 4/20 | 0.32 |
| ▸ | CCR2 | P41597 | 3/20 | 0.32 |
| ▸ | CCR5 | P51681 | 2/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | BPTF | Q12830 | 1/20 | 0.30 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29488641 | 0.81 | PTGDR2 (0.36) | PTGDR2 | |
| SCHEMBL29488643 | 0.78 | PTGS2 (0.38) | PTGDR2 | |
| SCHEMBL29488651 | 0.75 | DPP4 (0.37) | CCR2CCR5 | |
| SCHEMBL29488656 | 0.74 | PTGDR2 (0.53) | PTGDR2 | |
| SCHEMBL24820997 | 0.73 | MAPT (0.38) | THRATHRBABL1SRC | |
| SCHEMBL24821078 | 0.73 | THRA (0.65) | THRATHRB | |
| SCHEMBL29488652 | 0.73 | DPP4 (0.36) | CCR2CCR5ABL1SRC | |
| SCHEMBL29488655 | 0.73 | GAA (0.43) | SRC | |
| SCHEMBL23370058 | 0.71 | POLB (0.36) | — | |
| SCHEMBL29488649 | 0.70 | MAPT (0.40) | THRBPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022068915-A1 | 6-OXO-1,6-DIHYDROPYRIDAZIN DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF IN MEDICINE | 江苏恒瑞医药股份有限公司 | 2022-04-07 | — | — | WO | disclosed |