Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.34 |
| ▸ | ABL1 | P00519 | 3/20 | 0.34 |
| ▸ | EGFR | P00533 | 3/20 | 0.34 |
| ▸ | HCK | P08631 | 3/20 | 0.34 |
| ▸ | SRC | P12931 | 3/20 | 0.34 |
| ▸ | KDR | P35968 | 3/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.34 |
| ▸ | MTOR | P42345 | 3/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.34 |
| ▸ | EPHB4 | P54760 | 3/20 | 0.34 |
| ▸ | PRKDC | P78527 | 3/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29488651 | 0.95 | DPP4 (0.37) | DPP4DPP8DPP9KCNH2CCR2 | |
| SCHEMBL29488641 | 0.75 | PTGDR2 (0.36) | CYP2D6CYP3A4 | |
| SCHEMBL29488640 | 0.75 | THRA (0.59) | LMNASMN1; SMN2PDE9A | |
| SCHEMBL29488647 | 0.73 | THRA (0.32) | ABL1SRCCCR2CCR5 | |
| SCHEMBL29488643 | 0.73 | PTGS2 (0.38) | CYP2D6LMNACYP3A4 | |
| SCHEMBL29488655 | 0.70 | GAA (0.43) | SRCLMNASMN1; SMN2 | |
| SCHEMBL29488657 | 0.69 | THRA (0.57) | LMNASMN1; SMN2 | |
| SCHEMBL24821005 | 0.69 | MAPT (0.35) | DPP4DPP8DPP9KCNH2CYP2D6 | |
| SCHEMBL29488656 | 0.69 | PTGDR2 (0.53) | CYP2D6CYP3A4SMN1; SMN2 | |
| SCHEMBL29488649 | 0.68 | MAPT (0.40) | CYP2D6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022068915-A1 | 6-OXO-1,6-DIHYDROPYRIDAZIN DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF IN MEDICINE | 江苏恒瑞医药股份有限公司 | 2022-04-07 | — | — | WO | disclosed |