Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | HPGD | P15428 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22862805 | 1.00 | ALDH1A1 (0.50) | ALDH1A1HPGDKMT2AGAAMEN1 | |
| SCHEMBL22862474 | 0.91 | ALDH1A1 (0.59) | ALDH1A1HPGDKMT2AGAAMEN1 | |
| SCHEMBL29490285 | 0.91 | ALDH1A1 (0.59) | ALDH1A1HPGDKMT2AGAAMEN1 | |
| SCHEMBL22862477 | 0.82 | ALDH1A1 (0.37) | ALDH1A1HPGDKMT2AGAAMEN1 | |
| SCHEMBL3352559 | 0.78 | ALDH1A1 (0.53) | ALDH1A1HPGDKMT2AGAAMEN1 | |
| SCHEMBL3358563 | 0.78 | ALDH1A1 (0.51) | ALDH1A1HPGDKMT2AGAAMEN1 | |
| SCHEMBL22862454 | 0.76 | GAA (0.53) | ALDH1A1HPGDKMT2AGAAMEN1 | |
| SCHEMBL29490273 | 0.76 | GAA (0.53) | ALDH1A1HPGDKMT2AGAAMEN1 | |
| SCHEMBL3357708 | 0.75 | ALDH1A1 (0.58) | ALDH1A1HPGDKMT2AGAAMEN1 | |
| SCHEMBL30497269 | 0.74 | GAA (0.70) | ALDH1A1HPGDKMT2AGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3976009-A2 | BAX INHIBITORS AND USES THEREOF | Case Western Reserve University (US) | 2022-04-06 | — | — | EP | disclosed |