Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | FLT3 | P36888 | 4/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 4/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3357708 | 0.88 | ALDH1A1 (0.58) | ALDH1A1HPGDGAAMEN1KMT2A | |
| SCHEMBL3358563 | 0.87 | ALDH1A1 (0.51) | ALDH1A1HPGDGAAMEN1KMT2A | |
| SCHEMBL3354699 | 0.85 | ALDH1A1 (0.55) | ALDH1A1HPGDGAAMEN1KMT2A | |
| SCHEMBL3352200 | 0.83 | GAA (0.61) | ALDH1A1HPGDGAAMEN1KMT2A | |
| SCHEMBL4293328 | 0.82 | FLT3 (0.48) | ALDH1A1HPGDGAAMEN1KMT2A | |
| SCHEMBL14852148 | 0.79 | FLT3 (0.45) | ALDH1A1HPGDGAAMEN1KMT2A | |
| SCHEMBL31208292 | 0.79 | ALDH1A1 (0.60) | ALDH1A1HPGDGAAMEN1KMT2A | |
| SCHEMBL24075008 | 0.78 | HPGD (0.49) | ALDH1A1HPGDGAAMEN1KMT2A | |
| SCHEMBL22862805 | 0.78 | ALDH1A1 (0.50) | ALDH1A1HPGDGAAMEN1KMT2A | |
| SCHEMBL29490253 | 0.78 | ALDH1A1 (0.50) | ALDH1A1HPGDGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |