Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.58 |
| ▸ | HPGD | P15428 | 6/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3352559 | 0.88 | ALDH1A1 (0.53) | ALDH1A1HPGDGAAMEN1KMT2A | |
| SCHEMBL3358563 | 0.84 | ALDH1A1 (0.51) | ALDH1A1HPGDGAAMEN1KMT2A | |
| SCHEMBL3356723 | 0.83 | GAA (0.69) | ALDH1A1HPGDGAAMEN1KMT2A | |
| SCHEMBL3354699 | 0.82 | ALDH1A1 (0.55) | ALDH1A1HPGDGAAMEN1KMT2A | |
| SCHEMBL3356727 | 0.76 | GAA (0.49) | ALDH1A1HPGDGAAMEN1KMT2A | |
| SCHEMBL31208292 | 0.76 | ALDH1A1 (0.60) | ALDH1A1HPGDGAAMEN1KMT2A | |
| SCHEMBL29490253 | 0.75 | ALDH1A1 (0.50) | ALDH1A1HPGDGAAMEN1KMT2A | |
| SCHEMBL22862805 | 0.75 | ALDH1A1 (0.50) | ALDH1A1HPGDGAAMEN1KMT2A | |
| SCHEMBL3356346 | 0.74 | DDB1 (0.49) | ALDH1A1HPGDGAAMEN1KMT2A | |
| SCHEMBL24075008 | 0.73 | HPGD (0.49) | ALDH1A1HPGDGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |