Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | UBE2N | P61088 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PARG | Q86W56 | 1/20 | 0.34 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22862559 | 1.00 | THRB (0.40) | THRBSMN1; SMN2L3MBTL1TSHRTP53 | |
| SCHEMBL22862944 | 0.85 | MAPK14 (0.38) | THRBSMN1; SMN2L3MBTL1TSHRTP53 | |
| SCHEMBL22862520 | 0.85 | GABRG2 (0.36) | L3MBTL1TP53PDE1CPOLBLMNA | |
| SCHEMBL22862432 | 0.85 | MAPK14 (0.42) | SMN1; SMN2L3MBTL1TSHRRXFP1PDE1C | |
| SCHEMBL29490284 | 0.85 | MAPK14 (0.42) | SMN1; SMN2L3MBTL1TSHRRXFP1PDE1C | |
| SCHEMBL22862994 | 0.84 | KDM4E (0.37) | THRBSMN1; SMN2L3MBTL1TSHRTP53 | |
| SCHEMBL22862777 | 0.84 | KDM4E (0.37) | THRBSMN1; SMN2L3MBTL1TSHRTP53 | |
| SCHEMBL22862584 | 0.84 | THRB (0.40) | THRBSMN1; SMN2L3MBTL1TSHRTP53 | |
| SCHEMBL29490250 | 0.84 | THRB (0.40) | THRBSMN1; SMN2L3MBTL1TSHRTP53 | |
| SCHEMBL22862548 | 0.81 | POLB (0.45) | SMN1; SMN2L3MBTL1TSHRRXFP1PDE1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3976009-A2 | BAX INHIBITORS AND USES THEREOF | Case Western Reserve University (US) | 2022-04-06 | — | — | EP | disclosed |