Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29494467 | 0.82 | BAZ2B (0.44) | SMN1; SMN2NLRP3ALDH1A1NPC1MEN1 | |
| SCHEMBL29494480 | 0.82 | MEN1 (0.42) | SMN1; SMN2NLRP3ALDH1A1NPC1MEN1 | |
| SCHEMBL7233950 | 0.73 | SMN1; SMN2 (0.43) | SMN1; SMN2HPGDALDH1A1KDM4EALOX5 | |
| SCHEMBL18382971 | 0.73 | HTT (0.59) | SMN1; SMN2HPGDALDH1A1KDM4EMEN1 | |
| SCHEMBL31079645 | 0.71 | CASP1 (0.45) | SMN1; SMN2HPGDALDH1A1KDM4EALOX5 | |
| SCHEMBL10156668 | 0.71 | CASP1 (0.45) | SMN1; SMN2HPGDALDH1A1KDM4EALOX5 | |
| SCHEMBL23243065 | 0.71 | ALDH1A1 (0.45) | SMN1; SMN2HPGDALDH1A1KDM4EMEN1 | |
| SCHEMBL31079648 | 0.71 | ALDH1A1 (0.45) | SMN1; SMN2HPGDALDH1A1KDM4EMEN1 | |
| SCHEMBL15630970 | 0.71 | KDM4E (0.56) | SMN1; SMN2ALDH1A1KDM4EALOX5KMT2A | |
| SCHEMBL7610734 | 0.69 | GALR3 (0.56) | SMN1; SMN2HPGDALDH1A1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022070048-A1 | NOVEL AMIDE DERIVATIVES | CADILA HEALTHCARE LIMITED (IN) | 2022-04-07 | — | — | WO | claimed |
| WO-2022070048-A1 | NOVEL AMIDE DERIVATIVES | CADILA HEALTHCARE LIMITED (IN) | 2022-04-07 | — | — | WO | disclosed |