Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | RBP4 | P02753 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | FABP4 | P15090 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25354173 | 0.84 | NR1D1 (0.34) | MAT2AKDM4EALDH1A1LMNATSHR | |
| SCHEMBL25357731 | 0.81 | MAPT (0.44) | MAT2AKDM4EALDH1A1LMNATSHR | |
| SCHEMBL29494681 | 0.80 | NLRP3 (0.39) | KDM4EALDH1A1LMNATSHRBLM | |
| SCHEMBL25360067 | 0.78 | SLC22A12 (0.39) | KDM4EALDH1A1LMNATSHRBLM | |
| SCHEMBL25356856 | 0.78 | RECQL (0.37) | MAT2AKDM4EALDH1A1LMNATSHR | |
| SCHEMBL24077198 | 0.71 | ALOX15 (0.44) | MAT2AADORA2APRMT5WDR77MAPT | |
| SCHEMBL25355877 | 0.70 | NLRP3 (0.38) | MAT2AACSS2RBP4NR1D1PDE2A | |
| SCHEMBL24076917 | 0.65 | ALOX15 (0.62) | TSHRMAPTFABP4 | |
| SCHEMBL25354967 | 0.64 | ADORA2A (0.33) | KDM4EALDH1A1LMNATSHRBLM | |
| SCHEMBL25356861 | 0.64 | NLRP3 (0.57) | LMNAPDE2APTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3974415-A1 | NLRP3 MODULATORS | Janssen Pharmaceutica NV (BE) | 2022-03-30 | — | — | EP | disclosed |