Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25262955 | 1.00 | ACHE (0.44) | ACHEMEN1KMT2AMAPK1PDE4A | |
| SCHEMBL25395444 | 0.80 | TSHR (0.34) | ACHEMAPK1TSHRLMNAUSP2 | |
| SCHEMBL29495175 | 0.80 | TSHR (0.34) | ACHEMAPK1TSHRLMNAUSP2 | |
| SCHEMBL25259206 | 0.78 | ACHE (0.40) | ACHEMEN1KMT2AMAPK1TSHR | |
| SCHEMBL30198194 | 0.78 | ACHE (0.40) | ACHEMEN1KMT2AMAPK1TSHR | |
| SCHEMBL25374507 | 0.75 | KDM4E (0.46) | USP2ALDH1A1SMN1; SMN2NR3C1 | |
| SCHEMBL30552955 | 0.75 | KDM4E (0.46) | USP2ALDH1A1SMN1; SMN2NR3C1 | |
| SCHEMBL15054540 | 0.74 | LMNA (0.44) | MEN1KMT2AMAPK1TSHRLMNA | |
| SCHEMBL31698506 | 0.74 | MEN1 (0.45) | ACHEMEN1KMT2APDE4AADORA2A | |
| SCHEMBL23925485 | 0.73 | OPRK1 (0.43) | ALDH1A1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115443268-A | Benzimidazole derivatives | 豪夫迈·罗氏有限公司 | 2022-12-06 | — | — | CN | disclosed |