Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.38 |
| ▸ | C3AR1 | Q16581 | 2/20 | 0.34 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPY4R | P50391 | 5/20 | 0.33 |
| ▸ | GNPAT | O15228 | 1/20 | 0.32 |
| ▸ | NPY1R | P25929 | 3/20 | 0.32 |
| ▸ | NPY2R | P49146 | 3/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.31 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.31 |
| ▸ | ALB | P02768 | 2/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8517227 | 0.88 | FOLH1 (0.39) | FOLH1C3AR1NOD1SMN1; SMN2NPY4R | |
| SCHEMBL31184339 | 0.83 | FOLH1 (0.39) | FOLH1C3AR1NOD1SMN1; SMN2NPY4R | |
| SCHEMBL1724846 | 0.81 | FOLH1 (0.40) | FOLH1C3AR1NOD1SMN1; SMN2NPY4R | |
| SCHEMBL4552682 | 0.81 | FOLH1 (0.40) | FOLH1C3AR1NOD1SMN1; SMN2NPY4R | |
| SCHEMBL6026003 | 0.80 | FOLH1 (0.49) | FOLH1C3AR1NOD1SMN1; SMN2NPY4R | |
| SCHEMBL446929 | 0.80 | FOLH1 (0.49) | FOLH1C3AR1NOD1SMN1; SMN2NPY4R | |
| SCHEMBL8678705 | 0.80 | FOLH1 (0.46) | FOLH1C3AR1NOD1SMN1; SMN2NPY4R | |
| SCHEMBL468901 | 0.80 | FOLH1 (0.49) | FOLH1C3AR1NOD1SMN1; SMN2NPY4R | |
| SCHEMBL30526285 | 0.80 | FOLH1 (0.49) | FOLH1C3AR1NOD1SMN1; SMN2NPY4R | |
| SCHEMBL1070699 | 0.79 | ALDH1A1 (0.41) | FOLH1C3AR1NOD1SMN1; SMN2NPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112154145-B | Piperazine azaspiro derivatives | 辉瑞大药厂 | 2023-10-17 | — | — | CN | disclosed |
| CN-107787322-B | Tricyclic compounds and their use as phosphodiesterase inhibitors | 辉瑞大药厂 | 2023-07-07 | — | — | CN | disclosed |
| CN-110944998-B | Dihydro-pyrrolo-pyridine derivatives | 辉瑞大药厂 | 2022-08-16 | — | — | CN | disclosed |
| CN-109641898-B | 5, 7-dihydro-pyrrolo-pyridine derivatives for the treatment of neurological and neurodegenerative diseases | 辉瑞公司 | 2022-04-08 | — | — | CN | disclosed |