SCHEMBL29496684

SCHEMBL29496684

CC(C)C[C@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CCCCN)C(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CS)C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ NTSR2 O95665 17/20 0.67
▸ NTSR1 P30989 17/20 0.67
▸ SORT1 Q99523 15/20 0.67
▸ OPRM1 P35372 1/20 0.61
▸ OPRD1 P41143 1/20 0.61
▸ OPRK1 P41145 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29725007 0.96 NTSR2 (0.71) NTSR2NTSR1SORT1OPRM1OPRD1
SCHEMBL31280899 0.89 NTSR1 (0.74) NTSR2NTSR1SORT1OPRM1OPRD1
SCHEMBL30623611 0.87 NTSR1 (0.65) NTSR2NTSR1SORT1OPRM1OPRD1
SCHEMBL30294171 0.86 NTSR1 (0.64) NTSR2NTSR1SORT1OPRM1OPRD1
SCHEMBL29414469 0.85 NTSR1 (0.62) NTSR2NTSR1SORT1OPRM1OPRD1
SCHEMBL31018333 0.85 CALCR (0.55) NTSR2NTSR1SORT1OPRM1OPRD1
SCHEMBL29940473 0.85 NTSR1 (0.64) NTSR2NTSR1SORT1OPRM1OPRD1
SCHEMBL29361023 0.84 NTSR1 (0.74) NTSR2NTSR1SORT1OPRM1OPRD1
SCHEMBL30361896 0.84 NTSR1 (0.61) NTSR2NTSR1SORT1OPRM1OPRD1
SCHEMBL31151633 0.84 NTSR1 (0.61) NTSR2NTSR1SORT1OPRM1OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4700117-A2 COMPOSITIONS AND METHODS FOR THE TREATMENT OF ISCHEMIA AND CARDIOMYOPATHY Summa Health (US) 2026-02-25 — — EP disclosed
US-12365876-B2 Genetically modified stem cells SDF BioPharma (US) 2025-07-22 — — US disclosed
US-20250041325-A1 LIPID-BASED COMPOSITIONS AND METHODS THEREOF UNITED STATES GOVERNMENT 2025-02-06 — — US disclosed
US-20240360418-A1 METHODS FOR REDUCING ELEVATED GLUCOSE LEVELS SDF BIOPHARMA INC. 2024-10-31 — — US disclosed
US-12122844-B2 Treatment of brain cancers using central nervous system mediated gene transfer of monoclonal antibodies CORNELL UNIVERSITY (US) 2024-10-22 — — US disclosed
US-20240228586-A1 COMPOSITIONS AND METHODS COMPRISING PROTEASE-ACTIVATED THERAPEUTIC AGENTS THE UNIVERSITY OF CHICAGO (US) 2024-07-11 — — US disclosed
US-12024568-B2 Treatment of brain cancers using central nervous system mediated gene transfer of monoclonal antibodies CORNELL UNIVERSITY (US) 2024-07-02 — — US disclosed
US-11981928-B2 Methods for reducing elevated glucose levels SDF BIOPHARMA INC. (US) 2024-05-14 — — US disclosed
US-20240150722-A1 GENETICALLY MODIFIED STEM CELLS SDF BIOPHARMA INC. 2024-05-09 — — US disclosed
US-20240139376-A1 RECONSTITUTION OF EXTRACELLULAR MATRIXES FOR MUSCULOSKELETAL JOINT TISSUE REPAIR USING BIOMIMETIC BIOLOGIC AND SYNTHETIC FACTORS RHODE ISLAND HOSPITAL 2024-05-02 — — US disclosed
US-11857631-B2 Protection and delivery of multiple therapeutic proteins University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2024-01-02 — — US disclosed
US-11739298-B2 Genetically modified stem cells SDF BIOPHARMA INC. (US) 2023-08-29 — — US disclosed
WO-2023107574-A2 LIPID-BASED COMPOSITIONS AND METHODS THEREOF THE BRIGHAM AND WOMEN’S HOSPITAL, INC. (US) 2023-06-15 — — WO disclosed
US-20230149511-A1 TREATING AUTOIMMUNE DISEASES WITH GENETICALLY MODIFIED CELLS Wallkill BioPharma, Inc. 2023-05-18 — — US disclosed
US-20220281936-A1 COMPOSITIONS AND METHODS COMPRISING PROTEASE-ACTIVATED THERAPEUTIC AGENTS THE UNIVERSITY OF CHICAGO (US) 2022-09-08 — — US disclosed
WO-2022174071-A2 RECONSTITUTION OF EXTRACELLULAR MATRIXES FOR MUSCULOSKELETAL JOINT TISSUE REPAIR USING BIOMIMETIC BIOLOGIC AND SYNTHETIC FACTORS RHODE ISLAND HOSPITAL (US) 2022-08-18 — — WO disclosed
US-20220249672-A1 Protection and Delivery of Multiple Therapeutic Proteins UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION 2022-08-11 — — US disclosed
WO-2022140781-A1 USE OF STROMAL CELL-DERIVED FACTOR 1 (SDF1) AS A BIOMARKER FOR DIAGNOSING AND TREATING SEVERE ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS) ANN AND ROBERT H. LURIE CHILDREN'S HOSPITAL OF CHICAGO (US) 2022-06-30 — — WO disclosed
US-20220145262-A1 GENETICALLY MODIFIED STEM CELLS SDF BIOPHARMA INC. (US) 2022-05-12 — — US disclosed
US-11298423-B2 Protection and delivery of multiple therapeutic proteins University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2022-04-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240228586-A1 COMPOSITIONS AND METHODS COMPRISING PROTEASE-ACTIVATED THERAPEUTIC AGENTS ADAM8, COL14A1, COL2A1 NTSR2 4026/4885NTSR1 3229/4885SORT1 694/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback