SCHEMBL29725007

SCHEMBL29725007

CC(C)C[C@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CCCCN)C(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)O

nearest known ligand 0.71

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ NTSR2 O95665 16/20 0.71
▸ NTSR1 P30989 16/20 0.71
▸ SORT1 Q99523 14/20 0.71
▸ F2 P00734 1/20 0.62
▸ OPRM1 P35372 1/20 0.62
▸ OPRD1 P41143 1/20 0.62
▸ OPRK1 P41145 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29496684 0.96 NTSR2 (0.67) NTSR2NTSR1SORT1OPRM1OPRD1
SCHEMBL31280899 0.91 NTSR1 (0.74) NTSR2NTSR1SORT1OPRM1OPRD1
SCHEMBL30623611 0.88 NTSR1 (0.65) NTSR2NTSR1SORT1OPRM1OPRD1
SCHEMBL30294171 0.87 NTSR1 (0.64) NTSR2NTSR1SORT1OPRM1OPRD1
SCHEMBL29361023 0.87 NTSR1 (0.74) NTSR2NTSR1SORT1OPRM1OPRD1
SCHEMBL29414469 0.87 NTSR1 (0.62) NTSR2NTSR1SORT1OPRM1OPRD1
SCHEMBL29940473 0.86 NTSR1 (0.64) NTSR2NTSR1SORT1OPRM1OPRD1
SCHEMBL31411493 0.86 NTSR1 (0.62) NTSR2NTSR1SORT1OPRM1OPRD1
SCHEMBL30361896 0.85 NTSR1 (0.61) NTSR2NTSR1SORT1OPRM1OPRD1
SCHEMBL31151633 0.85 NTSR1 (0.61) NTSR2NTSR1SORT1OPRM1OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026106981-A1 IMMUNOCYTOKINES FOR HEART FAILURE PREVENTION THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2026-05-21 — — WO disclosed
EP-3377103-B2 FUNCTIONAL ANTIBODY FRAGMENT COMPLEMENTATION FOR A TWO-COMPONENTS SYSTEM FOR REDIRECTED KILLING OF UNWANTED CELLS REVITOPE LTD (GB) 2025-03-12 — — EP disclosed
CN-119139561-A Phage composite hydrogel, preparation method thereof and application thereof in promoting alveolar bone repair 浙江大学 2024-12-17 — — CN disclosed
US-20240228586-A1 COMPOSITIONS AND METHODS COMPRISING PROTEASE-ACTIVATED THERAPEUTIC AGENTS THE UNIVERSITY OF CHICAGO (US) 2024-07-11 — — US disclosed
US-20230399415-A1 Twin Immune Cell Engager REVITOPE LIMITED (GB) 2023-12-14 — — US disclosed
US-11702482-B2 Twin immune cell engager REVITOPE LIMITED (GB) 2023-07-18 — — US disclosed
US-11590198-B2 Methods and reagents for efficient and targeted delivery of therapeutic molecules to CXCR4 cells UNIVERSITAT AUTONOMA DE BARCELONA (ES) 2023-02-28 — — US disclosed
US-20220323600-A1 TEAC AND ATTAC IMMUNOONCOLOGY COMPOSITIONS AND METHODS REVITOPE LIMITED (GB) 2022-10-13 — — US disclosed
US-20220281936-A1 COMPOSITIONS AND METHODS COMPRISING PROTEASE-ACTIVATED THERAPEUTIC AGENTS THE UNIVERSITY OF CHICAGO (US) 2022-09-08 — — US disclosed
US-20220259386-A1 SUPRAMOLECULAR HYDROGELS TECHNISCHE UNIVERSITEIT EINDHOVEN (NL) 2022-08-18 — — US disclosed
US-11369662-B2 Methods of treating inflammation with monomeric CXCL12 peptide THE MEDICAL COLLEGE OF WISCONSIN, INC. (US) 2022-06-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220259386-A1 SUPRAMOLECULAR HYDROGELS UROD, FGB, UACA NTSR2 4517/4885NTSR1 4032/4885SORT1 3633/4885
US-20240228586-A1 COMPOSITIONS AND METHODS COMPRISING PROTEASE-ACTIVATED THERAPEUTIC AGENTS ADAM8, COL14A1, COL2A1 NTSR2 4026/4885NTSR1 3229/4885SORT1 694/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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