SCHEMBL29496724

SCHEMBL29496724

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nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ CA2 P00918 1/20 0.46
▸ CA4 P22748 1/20 0.46
▸ TERT O14746 1/20 0.43
▸ EPHX2 P34913 2/20 0.40
▸ PTGS1 P23219 1/20 0.40
▸ GSTK1 Q9Y2Q3 1/20 0.40
▸ NOD1 Q9Y239 1/20 0.40
▸ ENPEP Q07075 5/20 0.40
▸ ECE1 P42892 1/20 0.39
▸ MME P08473 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15929901 0.89 NOD1 (0.42) TERTPTGS1GSTK1NOD1ENPEP
SCHEMBL29429287 0.89 ECE1 (0.51) CA2TERTPTGS1GSTK1NOD1
SCHEMBL30997361 0.86 FNTA (0.44) —
SCHEMBL30662551 0.85 CA2 (0.47) CA2CA4EPHX2PTGS1GSTK1
SCHEMBL29351781 0.85 MME (0.47) TERTPTGS1GSTK1NOD1MME
SCHEMBL31402734 0.85 NOD1 (0.46) PTGS1GSTK1NOD1ENPEPECE1
SCHEMBL29544382 0.85 MME (0.44) CA2CA4EPHX2PTGS1GSTK1
SCHEMBL30662550 0.84 FOLH1 (0.50) PTGS1GSTK1NOD1
SCHEMBL29590916 0.84 ALDH1A1 (0.51) TERTMME
SCHEMBL29373113 0.84 ACE (0.53) TERTPTGS1GSTK1NOD1ENPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11857631-B2 Protection and delivery of multiple therapeutic proteins University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2024-01-02 — — US claimed
US-20220249672-A1 Protection and Delivery of Multiple Therapeutic Proteins UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION 2022-08-11 — — US claimed
US-20240124517-A1 METHOD FOR PRODUCING PEPTIDE COMPOUND CONTAINING N-SUBSTITUTED-AMINO ACID RESIDUE CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-04-18 — — US disclosed
US-11857631-B2 Protection and delivery of multiple therapeutic proteins University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2024-01-02 — — US disclosed
EP-4269422-A1 METHOD FOR PRODUCING PEPTIDE COMPOUND CONTAINING N-SUBSTITUTED-AMINO ACID RESIDUE CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2023-11-01 — — EP disclosed
US-11779647-B2 Complex coacervate for controlled release and related methods University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2023-10-10 — — US disclosed
US-20220249672-A1 Protection and Delivery of Multiple Therapeutic Proteins UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION 2022-08-11 — — US disclosed
WO-2022138891-A1 METHOD FOR PRODUCING PEPTIDE COMPOUND CONTAINING N-SUBSTITUTED-AMINO ACID RESIDUE 中外製薬株式会社 2022-06-30 — — WO disclosed
US-11298423-B2 Protection and delivery of multiple therapeutic proteins University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2022-04-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240124517-A1 METHOD FOR PRODUCING PEPTIDE COMPOUND CONTAINING N-SUBSTITUTED-AMINO ACID RESIDUE VIP, NPEPPS, ANPEP CA2 4388/4885CA4 3285/4885TERT 1145/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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