Aceprometazine

Aceprometazine

SCHEMBL29497450

CC(=O)c1ccc2c(c1)N(CC(C)N(C)C)c1ccccc1S2

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 7/20 0.79
ADRA1A P35348 7/20 0.79
DRD3 P35462 7/20 0.79
KCNH2 Q12809 7/20 0.79
CHRM2 P08172 6/20 0.79
CHRM1 P11229 6/20 0.79
DRD2 P14416 5/20 0.79
OPRM1 P35372 5/20 0.79
ADRA2B P18089 4/20 0.79
ADRA2C P18825 4/20 0.79
HTR2A P28223 4/20 0.79
HRH1 P35367 4/20 0.79
HTR2B P41595 4/20 0.79
CHRM3 P20309 3/20 0.79
HTR2C P28335 3/20 0.79
OPRK1 P41145 3/20 0.79
CYP2D6 P10635 7/20 0.69
SLC6A2 P23975 6/20 0.69
SLC6A4 P31645 6/20 0.69
ADRA2A P08913 5/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aceprometazine SCHEMBL29688253 1.00 HTR1A (0.79) HTR1AADRA1ADRD3KCNH2CHRM2
Aceprometazine SCHEMBL11491734 1.00 HTR1A (0.79) HTR1AADRA1ADRD3KCNH2CHRM2
Aceprometazine SCHEMBL142393 1.00 HTR1A (0.79) HTR1AADRA1ADRD3KCNH2CHRM2
SCHEMBL10368273 0.91 CHRM2 (0.79) HTR1AADRA1ADRD3KCNH2CHRM2
Propiomazine SCHEMBL29370554 0.88 CHRM2 (1.00) HTR1AADRA1ADRD3KCNH2CHRM2
(R)-Propiomazine SCHEMBL6910697 0.88 CHRM2 (1.00) HTR1AADRA1ADRD3KCNH2CHRM2
Propiomazine SCHEMBL93770 0.88 CHRM2 (1.00) HTR1AADRA1ADRD3KCNH2CHRM2
Propiomazine SCHEMBL29609596 0.88 CHRM2 (1.00) HTR1AADRA1ADRD3KCNH2CHRM2
Propiomazine SCHEMBL6372719 0.87 CHRM2 (0.98) HTR1AADRA1ADRD3KCNH2CHRM2
Propiomazine SCHEMBL141677 0.87 CHRM2 (0.98) HTR1AADRA1ADRD3KCNH2CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12324435-B2 Combination of novel nitrification inhibitors and herbicides as well as combination of (thio)phosphoric acid triamides and herbicides BASF SE (DE) 2025-06-10 US disclosed
US-20220117231-A1 Combination of Novel Nitrification Inhibitors and Herbicides as Well as Combination of (Thio)Phosphoric Acid Triamides and Herbicides BASF SE (DE) 2022-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12324435-B2 Combination of novel nitrification inhibitors and herbicides as well as combination of (thio)phosphoric acid triamides and herbicides NMT2, NAPRT, NAMPT HTR1A 3202/4885ADRA1A 4306/4885DRD3 2775/4885
US-20220117231-A1 Combination of Novel Nitrification Inhibitors and Herbicides as Well as Combination of (Thio)Phosphoric Acid Triamides and Herbicides NMT2, NAPRT, NAMPT HTR1A 3202/4885ADRA1A 4306/4885DRD3 2775/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.