Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Trifluoromethanesulfonic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRB | P28702 | 6/20 | 0.37 |
| ▸ | RXRA | P19793 | 5/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | PGK1 | P00558 | 1/20 | 0.33 |
| ▸ | PGK2 | P07205 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoromethanesulfonic Acid SCHEMBL30131110 | 0.85 | CA1 (0.35) | CA1CA2MMP1MMP2MMP9 | |
| Trifluoromethanesulfonic Acid SCHEMBL30892598 | 0.85 | HSD17B2 (0.35) | RXRBRXRAHSD17B2RXRGCA1 | |
| SCHEMBL30083766 | 0.82 | POLB (0.43) | RXRBRXRARXRGCA2MAPT | |
| Trifluoromethanesulfonic Acid SCHEMBL30131107 | 0.74 | RAPGEF4 (0.45) | CA1CA2MMP1MMP2MMP9 | |
| Trifluoromethanesulfonic Acid SCHEMBL30131108 | 0.74 | FFAR4 (0.47) | RXRBRXRAMAPTALDH1A1 | |
| Trifluoromethanesulfonic Acid SCHEMBL29181639 | 0.72 | PGK1 (0.40) | CA1CA2MMP1MMP2MMP9 | |
| Trifluoromethanesulfonic Acid SCHEMBL30131114 | 0.71 | PDK2 (0.39) | CA1CA2CYP3A4MAPTMAPK1 | |
| Trifluoromethanesulfonic Acid SCHEMBL7089707 | 0.70 | GABRA1 (0.39) | RXRBRXRAHSD17B2RXRGACLY | |
| Trifluoromethanesulfonic Acid SCHEMBL29195610 | 0.70 | CA1 (0.38) | CA1CA2MMP1MMP2MMP9 | |
| Trifluoromethanesulfonic Acid SCHEMBL29380598 | 0.70 | CA1 (0.38) | CA1CA2MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114195828-A | Organometallic compound, organic light emitting device including the same, and diagnostic composition including the organometallic compound | 三星电子株式会社 | 2022-03-18 | — | — | CN | disclosed |