Trifluoromethanesulfonic Acid

Trifluoromethanesulfonic Acid

SCHEMBL30131107

Cc1cc(C)c(-c2ccc(I)cc2)c(C)c1.O=S(=O)(O)C(F)(F)F

nearest known ligand 0.45

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 3/20 0.45
PTGS2 P35354 4/20 0.33
PDK2 Q15119 1/20 0.33
PTPN1 P18031 2/20 0.33
CYP1A2 P05177 2/20 0.32
CYP3A4 P08684 2/20 0.32
CYP2C19 P33261 2/20 0.32
MEN1 O00255 1/20 0.32
CYP2D6 P10635 1/20 0.32
TSHR P16473 1/20 0.32
KMT2A Q03164 1/20 0.32
FFAR4 Q5NUL3 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
MMP1 P03956 1/20 0.32
MMP2 P08253 1/20 0.32
MMP9 P14780 1/20 0.32
MMP8 P22894 1/20 0.32
MMP13 P45452 1/20 0.32
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26463825 0.81 RAPGEF4 (0.47) RAPGEF4PTGS2CYP1A2CYP3A4MEN1
Trifluoromethanesulfonic Acid SCHEMBL30131108 0.81 FFAR4 (0.47) FFAR4MAPT
Trifluoromethanesulfonic Acid SCHEMBL30131110 0.80 CA1 (0.35) RAPGEF4PDK2CYP1A2CYP3A4CYP2C19
Trifluoromethanesulfonic Acid SCHEMBL3347804 0.79 CA2 (0.42) RAPGEF4PTGS2MEN1KMT2ACA1
Trifluoromethanesulfonic Acid SCHEMBL29195610 0.78 CA1 (0.38) RAPGEF4CYP1A2CYP3A4CYP2C19MEN1
Trifluoromethanesulfonic Acid SCHEMBL30131109 0.77 HTT (0.42) PTPN1CYP1A2CYP2C19MMP1MMP9
Trifluoromethanesulfonic Acid SCHEMBL28750655 0.77 CA1 (0.43) PTPN1CA1CA2MMP1MMP2
Trifluoromethanesulfonic Acid SCHEMBL29498397 0.74 RXRB (0.37) RAPGEF4PTPN1CYP1A2CYP3A4CYP2C19
Trifluoromethanesulfonic Acid SCHEMBL8734882 0.73 KCNH2 (0.38) PTGS2PTPN1MEN1KMT2AFFAR4
Trifluoromethanesulfonic Acid SCHEMBL29181639 0.73 PGK1 (0.40) RAPGEF4PTGS2PTPN1CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111410603-B Benzanthrone derivative, preparation method thereof and application thereof in functional pigment 上海甘田光学材料有限公司 2022-12-16 CN disclosed