Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 6/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 6/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29499365 | 0.83 | ADORA2A (0.46) | ADORA1ADORA2AADORA2BADORA3MEN1 | |
| SCHEMBL29499333 | 0.76 | ADORA1 (0.44) | ADORA1ADORA2AADORA2BADORA3MEN1 | |
| SCHEMBL15329912 | 0.72 | CYP1A2 (0.35) | CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5812520 | 0.66 | L3MBTL1 (0.52) | ADORA2AADORA3MEN1KMT2A | |
| SCHEMBL7833731 | 0.64 | PDE4A (0.41) | ADORA1ADORA2AADORA2BMEN1KMT2A | |
| SCHEMBL29499309 | 0.64 | ADORA2A (0.43) | ADORA1ADORA2AADORA2BADORA3MEN1 | |
| SCHEMBL14927481 | 0.63 | PGR (0.47) | ADORA1ADORA2AADORA2BADORA3MEN1 | |
| SCHEMBL10085643 | 0.62 | ALDH1A1 (0.45) | ADORA1ADORA2AADORA2BMEN1KMT2A | |
| SCHEMBL11152903 | 0.62 | ALDH1A1 (0.41) | MEN1KMT2APDE4APDE4BPDE4C | |
| SCHEMBL21900263 | 0.62 | CDK9 (0.44) | ADORA2BKMT2AALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022048498-A1 | USP7 INHIBITOR | 首药控股(北京)股份有限公司 | 2022-03-10 | — | — | WO | disclosed |