Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NMT1 | P30419 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25255731 | 1.00 | KDM4E (0.49) | KDM4EHSD17B10GAAL3MBTL1ALDH1A1 | |
| SCHEMBL9370802 | 0.85 | KDM4E (0.50) | KDM4EHSD17B10GAAL3MBTL1ALDH1A1 | |
| SCHEMBL16166523 | 0.79 | KDM4E (0.55) | KDM4EHSD17B10GAAL3MBTL1ALDH1A1 | |
| SCHEMBL28166126 | 0.79 | KDM4E (0.46) | KDM4EHSD17B10GAAL3MBTL1ALDH1A1 | |
| SCHEMBL3876573 | 0.77 | ALDH1A1 (0.53) | KDM4EL3MBTL1ALDH1A1MAPTNMT1 | |
| SCHEMBL612735 | 0.77 | KDM4E (0.51) | KDM4EHSD17B10GAAL3MBTL1ALDH1A1 | |
| SCHEMBL3588853 | 0.75 | POLB (0.49) | KDM4EL3MBTL1ALDH1A1MAPTTSHR | |
| SCHEMBL277286 | 0.75 | CYP2C9 (0.54) | KDM4EHSD17B10ALDH1A1MAPTTSHR | |
| SCHEMBL12458000 | 0.75 | CA12 (0.56) | KDM4EHSD17B10GAAL3MBTL1ALDH1A1 | |
| SCHEMBL5164025 | 0.74 | TDP1 (0.47) | KDM4EHSD17B10GAAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4208464-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | Syngenta Crop Protection AG (CH) | 2023-07-12 | — | — | EP | disclosed |
| CN-116075226-A | Pesticidally active heterocyclic derivatives with sulfur containing substituents | 先正达农作物保护股份公司 | 2023-05-05 | — | — | CN | disclosed |
| WO-2022049144-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA CROP PROTECTION AG (CH) | 2022-03-10 | — | — | WO | disclosed |