Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.42 |
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10341448 | 1.00 | MET (0.50) | METPAX8KDM1AMAOBPOLB | |
| SCHEMBL11628722 | 0.86 | L3MBTL1 (0.47) | KDM1AMAOBPOLBSMN1; SMN2HTT | |
| SCHEMBL30133412 | 0.80 | L3MBTL1 (0.52) | KDM1AMAOBPOLBSMN1; SMN2HTT | |
| SCHEMBL6935609 | 0.79 | FGFR1 (0.45) | LMNA | |
| SCHEMBL2232473 | 0.79 | MET (0.50) | METPAX8MAOBSMN1; SMN2CALM1 | |
| SCHEMBL19996089 | 0.79 | MET (0.46) | METPAX8MAOBPOLBSMN1; SMN2 | |
| SCHEMBL27706106 | 0.78 | CALM1 (0.42) | METPAX8POLBCALM1MEN1 | |
| SCHEMBL1564325 | 0.78 | MET (0.49) | METPAX8CALM1HTR2ALIMK2 | |
| SCHEMBL4859544 | 0.78 | PAX8 (0.56) | METPAX8CALM1MEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL28590384 | 0.78 | MET (0.49) | METPAX8MAOBSMN1; SMN2CALM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118475580-A | Platelet-derived growth factor receptor (PDGFR) alpha inhibitors and uses thereof | 普罗根托斯治疗公司 | 2024-08-09 | — | — | CN | disclosed |
| CN-110740646-B | Herbicidal mixtures, compositions and methods | FMC公司 | 2022-05-10 | — | — | CN | disclosed |