Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.54 |
| ▸ | CCR1 | P32246 | 2/20 | 0.51 |
| ▸ | CCR8 | P51685 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | MMP14 | P50281 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL462223 | 0.98 | LMNA (0.56) | LMNACCR1CCR8L3MBTL1ALDH1A1 | |
| SCHEMBL1615610 | 0.97 | LMNA (0.54) | LMNACCR1CCR8L3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2528246 | 0.97 | LMNA (0.54) | LMNACCR1CCR8L3MBTL1ALDH1A1 | |
| SCHEMBL3298981 | 0.94 | LMNA (0.51) | LMNACCR1CCR8L3MBTL1ALDH1A1 | |
| SCHEMBL28884057 | 0.84 | LMNA (0.52) | LMNACCR1CCR8L3MBTL1ALDH1A1 | |
| 1-Naphthoquinoline SCHEMBL4219087 | 0.78 | ALDH1A1 (0.64) | LMNACCR1CCR8L3MBTL1ALDH1A1 | |
| SCHEMBL29555797 | 0.78 | CCR1 (0.61) | LMNACCR1CCR8L3MBTL1ALDH1A1 | |
| SCHEMBL16467196 | 0.78 | CCR1 (0.61) | LMNACCR1CCR8L3MBTL1ALDH1A1 | |
| SCHEMBL15673966 | 0.77 | ALDH1A1 (0.56) | LMNAL3MBTL1ALDH1A1MAPTKDM4E | |
| SCHEMBL10923942 | 0.77 | LMNA (0.53) | LMNACCR1CCR8L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4073811-A | Process for the preparation of aldehydes | HOFFMANN-LA ROCHE INC. (US) | 1978-02-14 | — | — | US | claimed |
| EP-2746271-B1 | Phenyl-substituted 1, 3, 5-triazine compounds as intermediates for electroluminescent molecules | TOSOH CORP (JP) | 2016-08-17 | — | — | EP | disclosed |
| EP-2746271-A1 | Phenyl-substituted 1, 3, 5-triazine compounds as intermediates for electroluminescent molecules | Tosoh Corporation (JP) | 2014-06-25 | — | — | EP | disclosed |
| EP-2141158-B1 | PHENYL-SUBSTITUTED 1,3,5-TRIAZINE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND ORGANIC ELECTROLUMINESCENT DEVICE CONTAINING THE SAME AS COMPONENT | TOSOH CORP (JP) | 2014-05-07 | — | — | EP | disclosed |
| US-8268997-B2 | Phenyl-substituted 1,3,5-triazine compound, process for producing the same, and organic electroluminescent device containing the same as component | TOSOH CORPORATION (JP) | 2012-09-18 | — | — | US | disclosed |
| US-20100249406-A1 | PHENYL-SUBSTITUTED 1,3.5-TRIAZINE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND ORGANIC ELECTROLUMINESCENT DEVICE CONTAINING THE SAME AS COMPONENT | TOSOH CORPORATION (JP) | 2010-09-30 | — | — | US | disclosed |
| EP-2141158-A1 | PHENYL-SUBSTITUTED 1,3,5-TRIAZINE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND ORGANIC ELECTROLUMINESCENT DEVICE CONTAINING THE SAME AS COMPONENT | Tosoh Corporation (JP) | 2010-01-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249406-A1 | PHENYL-SUBSTITUTED 1,3.5-TRIAZINE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND ORGANIC ELECTROLUMINESCENT DEVICE CONTAINING THE SAME AS COMPONENT | H1-5, H1-4, H1-2 | LMNA 3818/4885CCR1 2985/4885CCR8 4529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.