Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 20/20 | 0.64 |
| ▸ | PDE4A | P27815 | 6/20 | 0.64 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.64 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1572501 | 1.00 | PDE4B (0.64) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6745558 | 0.99 | PDE4B (0.62) | PDE4BPDE4APDE4CPDE4D | |
| Lithium Ion SCHEMBL6745554 | 0.89 | PDE4B (0.58) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL6322653 | 0.84 | PDE4B (0.62) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7368562 | 0.81 | PDE4B (0.64) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7365058 | 0.79 | PDE4B (0.61) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL9167416 | 0.78 | PDE4B (0.78) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL5184039 | 0.78 | PDE4B (1.00) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL15040911 | 0.78 | PDE4B (1.00) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7370366 | 0.77 | PDE4B (0.59) | PDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110785420-B | Oxazepin derivatives as inhibitors of PI 3-kinase activity | 葛兰素史克知识产权开发有限公司 | 2022-04-26 | — | — | CN | disclosed |